Tag: Antimicrobial

Free Download Havard Jenssen, "Antimicrobial Activity of Lactoferrin and Lactoferrin Derived Peptides"
English | ISBN: 1606925180 | 2009 | 102 pages | PDF | 2 MB
Book by Jenssen, Havard

Free Download Antimicrobial Therapy in Veterinary Medicine
English | 2025 | ISBN: 1119654599 | 840 Pages | PDF, EPUB (True) | 25 MB
The sixth edition of Antimicrobial Therapy in Veterinary Medicine has been updated to reflect advances in the field, including new international contributors and a broader global outlook. It includes extensive knowledge of both general principles of mechanisms of antimicrobial drug action including specific classes of antimicrobial agents, as well as chapters dedicated to antimicrobial drug use in a wide range of animal species. As antimicrobial resistance increases as a major global issue in both human and animal health, this book’s renewed focus on antimicrobial stewardship in companion animals, in food animals, and on global aspects keeps it at the forefront of this vital field.

Free Download Evolution of Antimicrobial Peptides: From Self-Defense to Therapeutic Applications
English | 2024 | ISBN: 3031675142 | 635 Pages | PDF EPUB (True) | 24 MB
Over the last century, antibiotics have been a primary treatment for infectious diseases, and indiscriminate use by both healthcare providers and patients has led to the rapid emergence of resistant pathogens. Multidrug-resistant pathogens and infective agents are an urgent threat to global health, and this issue has created a critical need for the investigation of alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) have emerged as promising alternative therapeutics, with studies on their mechanisms and applications an area of intense interest in agricultural science, physiology, and medicine. AMPS are naturally occurring components of the host defense system, and functional throughout all orders of life, from prokaryotes to eukaryotes. They are potent molecules with broad spectrum activities against infectious agents, including bacteria, fungi, viruses, and parasites. AMPs have demonstrated therapeutic potential against non-infectious diseases like chronic inflammation and cancer, and have been found to have potential activities against slow-growing bacteria, such as biofilms.

Free Download Antimicrobial Resistance: Factors to Findings Omics and Systems Biology Approaches by Vijay Soni, Ajay Suresh Akhade
English | PDF EPUB (True) | 2024 | 459 Pages | ISBN : 3031659856 | 49.1 MB
Antimicrobial resistance (AMR) is increasing globally at an incredible rate, and many infectious diseases have already reached an alarming stage of resistance to existing treatments. WHO reports that nearly1.27 million people currently die each year due to resistant infections, and AMR is projected to account for 10 million annual deaths globally by 2050. There is an urgent need for novel approaches to address this issue. Omics technologies are powerful research tools used extensively to study pathogen biology and the activity of microbial agents. These tools, paired with systems biology approaches, can provide novel insights into antimicrobial susceptibility and resistance, and aid in the development of new, more effective measures to combat resistant pathogens.

Free Download Medicinal Plants and Antimicrobial Therapies by Vinay Kumar, Varsha Shriram, Abhijit Dey
English | January 5, 2024 | ISBN: 9819972604 | 233 pages | MOBI | 4.42 Mb
This book serves as an excellent comprehensive material covering the current understandings and updates on antimicrobial resistance (AMR) and the use of medicinal plant resources for tackling it. Chapters cover important aspects of AMR and strategies to address this threatening issue with medicinal plants and their resources. One health perspectives for addressing AMR have been presented for the readers. Antimicrobial medicinal plant therapeutic resources including crude extracts, active fractions, pure molecules and essential oils, besides using them as functionalizing agents for nano-antimicrobials have been covered. Further, plant endophytes as a source of antimicrobial compounds have been discussed. Chapters cover both the bactericidal as well as resistance-reversal (or potentiating/ combinatorial therapies) potencies of medicinal plant resources. The book also focuses on how medicinal plant resources effectively target major determinants of AMR. Use of metabolomics in understanding and targeting AMR mechanisms and identifying potent phyto-therapeutics has been discussed as well. The book is a valuable read for both experienced and younger researchers working in the field of AMR and related fields in biomedicine, pharmacy, and clinical research.

Free Download Antimicrobial Peptides from Lactic Acid Bacteria: Diversity, Biosynthesis and Applications
English | 2024 | ISBN: 9819734126 | 388 Pages | PDF EPUB (True) | 43 MB
Antimicrobial peptides (AMPs) have been sought to be a potential alternative to the current arsenal of antibiotics against undesirable microbes. AMPs synthesized by lactic acid bacteria have attracted significant attention due to their strong activity against a broad range of bacteria including pathogens. The bacteriocin (an AMP) has been known to us since early 1928, a year before penicillin was reported. This is possibly due to their narrower activity compared to antibiotics. However, several AMPs having promising activity have been thoroughly characterized in the past few decades. Renewed interest has developed focusing on industrially important bacteriocins produced by lactic acid bacteria. Some of these AMPs are also active against food spoilage and clinically important pathogens. Similar to antibiotics, large-scale intellectual screening is ongoing in the search for novel AMPs with unique properties. Recent research has revealed that AMPs may also play a role in maintaining gut microflora and keeping us protected from food-borne pathogens. The ongoing genomic studies suggest that there may be more such bioactive compounds waiting to be explored. This book provides an overview of the fundamental knowledge accumulated so far regarding the diversity and potential applications of AMPs produced by lactic acid bacteria. This updated reference book on AMPs from lactic acid bacteria is timely, covering the most important achievements in the field and providing the scientific community particularly graduate students, researchers, and clinicians with the latest updates. The goal of this book is to illustrate and detail the findings made so far, debate the state of the art, and draw new perspectives.

Free Download Ram Prasad, Busi Siddhardha, Madhu Dyavaiah, "Nanostructures for Antimicrobial and Antibiofilm Applications"
English | 2020 | pages: 461 | ISBN: 3030403394, 303040336X | PDF | 10,3 mb
In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications.

Free Download Antimicrobial Stewardship in Non-Traditional Settings: A Practical Guide by Shira Doron, Maureen Campion
English | March 2, 2023 | ISBN: 3031217098 | 228 pages | MOBI | 3.60 Mb
The evolution of Antimicrobial Resistance is outpacing the ability to create novel antibiotics, which is proving to be a global problem in the fact of climate change, population growth, demographic shifts toward aging populations, emerging infections, and other crises. Therefore, clinicians are forced to use the existing antimicrobials more responsibly to preserve their longevity for generations to come. In a parallel vein, there has been a recent regulatory acknowledgement of the importance of prudent antimicrobial prescribing, mandating the implementation of Antimicrobial Stewardship across all healthcare settings. This is harder to manage in a non-traditional setting, which include long-term care facilities, outpatient care clinics, urgent care centers, and others. Given the trends in patient care in these settings―particularly where the aging community is concerned―this is proving to be a growing problem. This is troublesome even for spaces that have university and large hospital affiliations.

Free Download Antimicrobial Stewardship in Non-Traditional Settings: A Practical Guide by Shira Doron, Maureen Campion
English | March 2, 2023 | ISBN: 3031217098 | 228 pages | MOBI | 3.60 Mb
The evolution of Antimicrobial Resistance is outpacing the ability to create novel antibiotics, which is proving to be a global problem in the fact of climate change, population growth, demographic shifts toward aging populations, emerging infections, and other crises. Therefore, clinicians are forced to use the existing antimicrobials more responsibly to preserve their longevity for generations to come. In a parallel vein, there has been a recent regulatory acknowledgement of the importance of prudent antimicrobial prescribing, mandating the implementation of Antimicrobial Stewardship across all healthcare settings. This is harder to manage in a non-traditional setting, which include long-term care facilities, outpatient care clinics, urgent care centers, and others. Given the trends in patient care in these settings―particularly where the aging community is concerned―this is proving to be a growing problem. This is troublesome even for spaces that have university and large hospital affiliations.

Free Download Antimicrobial Resistance in Agriculture and Its Consequences
English | 2024 | ISBN: 1032216441 | 205 Pages | PDF (True) | 6 MB
This book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobial resistance in agriculture and their applications in the fight against microbes. It discusses and compares biological, biochemical, and structural aspects of resistance and its evolution. This is a comprehensive tool covering all manifestations of antimicrobial resistance and microbial resistance genes. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. Novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target) molecule, are highly diverse and are covered in great detail.