Tag: Barriers

Free Download Everything But Money: The Hidden Barriers Between You and Financial Freedom by Jessica Moorhouse
English | December 31st, 2024 | ISBN: 1443472174 | 304 pages | True EPUB | 2.36 MB
Money therapy that goes beyond the budget and gets to the root of your relationship with money from accredited financial counsellor and host of the popular More Money Podcast, Jessica Moorhouse

Free Download Eric J. Scroggins, "Vision Blockers: How to Shatter Barriers to Achieve Your Destiny"
English | ISBN: 1940984084 | 2014 | 256 pages | EPUB | 470 KB
Overcome Your Vision Blockers and Embrace Your Future!

Free Download Ernest V. Burkheisser, "Biological Barriers to Cellulosic Ethanol "
English | ISBN: 1606922033 | 2009 | 251 pages | PDF | 17 MB
The purpose of this book is to define barriers and challenges to a rapid expansion of cellulosic-ethanol production and determine ways to speed solutions through concerted application of modern biology tools as part of a joint research agenda. Although the focus was ethanol, the science applies to additional fuels that include biodiesel and other bioproducts or coproducts having critical roles in any deployment scheme. The core barrier is cellulosic-biomass recalcitrance to processing to ethanol. Biomass is composed of nature’s most ready energy source, sugars, but they are locked in a complex polymer composite exquisitely created to resist biological and chemical degradation. Key to energising a new biofuel industry based on conversion of cellulose (and hemicelluloses) to ethanol is to understand plant cell-wall chemical and physical structures – how they are synthesised and can be deconstructed. With this knowledge, innovative energy crops – plants specifically designed for industrial processing to biofuel – can be developed concurrently with new biology-based treatment and conversion methods. Recent advances in science and technological capabilities, especially those from the nascent discipline of systems biology, promise to accelerate and enhance this development. Resulting technologies will create a fundamentally new process and biorefinery paradigm that will enable an efficient and economic industry for converting plant biomass to liquid fuels. These key barriers and suggested research strategies to address them are described in this book. The core barrier is cellulosic-biomass recalcitrance to processing to ethanol. Biomass is composed of nature’s most ready energy source, sugars, but they are locked in a complex polymer composite exquisitely created to resist biological and chemical degradation. Key to energising a new biofuel industry based on conversion of cellulose (and hemicelluloses) to ethanol is to understand plant cell-wall chemical and physical structures – how they are synthesised and can be deconstructed. With this knowledge, innovative energy crops – plants specifically designed for industrial processing to biofuel – can be developed concurrently with new biology-based treatment and conversion methods. Recent advances in science and technological capabilities, especially those from the nascent discipline of systems biology, promise to accelerate and enhance this development. Resulting technologies will create a fundamentally new process and biorefinery paradigm that will enable an efficient and economic industry for converting plant biomass to liquid fuels. These key barriers and suggested research strategies to address them are described in this book.

Free Download Empower Your Expertise: Breaking Barriers of Doubt by Lloyd Morfin
English | January 4, 2024 | ISBN: N/A | ASIN: B0CRN3HM28 | PDF | 1.99 Mb
Are you tired of feeling held back by your own doubts, despite your incredible skills and expertise?

Free Download Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1 By
2006 | 774 Pages | ISBN: 3527310886 | PDF | 8 MB
This first handbook to integrate developmental and cellular aspects combines the different structural and functional features involved in the regulation of brain perfusion and neuronal function. It highlights pharmacological and biomedical applications with sections on drug delivery and disease-related states as well as explaining in detail the role of astrocytes, shown to be an essential link between neurons and cerebral blood vessels. In addition the book studies how the structural elements interact in response to the dynamics of neuronal activities, necessitating adaptive mechanism of the interface. A significant part of the book describes new approaches to how the barrier can be surmised for drug delivery and how it can be mimicked by artificial in vitro systems for drug testing. Finally, the involvement of the barrier in brain diseases is considered, focusing on inflammatory and neurodegenerative disorders of the brain. Covering basic knowledge as well as specific information dealing with very recent progress in blood-brain interface research, this book will be of interest to a broad audience. Content: Chapter 1 Development of the Blood?Brain Interface (pages 9-39): Britta EngelhardtChapter 2 Brain Angiogenesis and Barriergenesis (pages 41-59): Jeong Ae Park, Yoon Kyung Choi, Sae?Won Lee and Kyu?Won KimChapter 3 Microvascular Influences on Progenitor Cell Mobilization and Fate in the Adult Brain (pages 61-74): Christina Lilliehook and Steven A. GoldmanChapter 4 The Endothelial Frontier (pages 75-107): Hartwig WolburgChapter 5 Pericytes and Their Contribution to the Blood?Brain Barrier (pages 109-127): Markus RamsauerChapter 6 Brain Macrophages: Enigmas and Conundrums (pages 129-165): Frederic Mercier, Sebastien Mambie and Glenn I. HattonChapter 7 The Microglial Component (pages 167-188): Ingo Bechmann, Angelika Rappert, Josef Priller and Robert NitschChapter 8 The Bipolar Astrocyte: Polarized Features of Astrocytic Glia Underlying Physiology, with Particular Reference to the Blood?Brain Barrier (pages 189-208): N. Joan AbbottChapter 9 Responsive Astrocytic Endfeet: The Role of AQP4 in BBB Development and Functioning (pages 209-236): Grazia P. Nicchia, Beatrice Nico, Laura M. A. Camassa, Maria G. Mola, Domenico Ribatti, David C. Spray, Alejandra Bosco, Maria Svelto and Antonio FrigeriChapter 10 The Role of Fibroblast Growth Factor 2 in the Establishment and Maintenance of the Blood?Brain Barrier (pages 237-246): Bernhard ReussChapter 11 Cytokines Interact with the Blood?Brain Barrier (pages 247-264): Weihong Pan, Shulin Xiang, Hong Tu and Abba J. KastinChapter 12 Insulin and the Blood?Brain Barrier (pages 265-285): William A. Banks and Wee Shiong LimChapter 13 Glucocorticoid Hormones and Estrogens: Their Interaction with the Endothelial Cells of the Blood?Brain Barrier (pages 287-312): Jean?Bernard DietrichChapter 14 Metalloproteinases and the Brain Microvasculature (pages 313-334): Dorothee Krause and Christina LohmannChapter 15 Modeling the Blood?Brain Barrier (pages 335-355): Romeo Cecchelli, Caroline Coisne, Lucie Dehouck, Florence Miller, Marie?Pierre Dehouck, Valerie Buee?Scherrer and Benedicte DehouckChapter 16 Induction of Blood?Brain Barrier Properties in Cultured Endothelial Cells (pages 357-374): Alla Zozulya, Christian Weidenfeller and Hans?Joachim GallaChapter 17 Artificial Blood?Brain Barriers (pages 375-401): Luca Cucullo, Emily Oby, Kerri Hallene, Barbara Aumayr, Ed Rapp and Damir JanigroChapter 18 In Silico Prediction Models for Blood?Brain Barrier Permeation (pages 403-428): Gerhard F. Ecker and Christian R. NoeChapter 19 The Blood?Brain Barrier: Roles of the Multidrug Resistance Transporter P?Glycoprotein (pages 429-461): Sandra Turcotte, Michel Demeule, Anthony Regina, Chantal Fournier, Julie Jodoin, Albert Moghrabi and Richard BeliveauChapter 20 Targeting of Neuropharmaceuticals by Chemical Delivery Systems (pages 463-500): Nicholas Bodor and Peter BuchwaldChapter 21 Drug Delivery to the Brain by Internalizing Receptors at the Blood?Brain Barrier (pages 501-520): Pieter J. Gaillard, Corine C. Visser and Albertus (Bert) G. de BoerChapter 22 Blood?Brain Transfer and Metabolism of Oxygen (pages 521-549): Albert GjeddeChapter 23 Functional Brain Imaging (pages 551-599): Gerald A. DienelChapter 24 Inflammatory Response of the Blood?Brain Interface (pages 601-618): Pedro M. Faustmann and Claus G. HaaseChapter 25 Stroke and the Blood?Brain Interface (pages 619-647): Marilyn J. CipollaChapter 26 Diabetes and the Consequences for the Blood?Brain Barrier (pages 649-669): Arshag D. MooradianChapter 27 Human Parasitic Disease in the Context of the Blood?Brain Barrier – Effects, Interactions, and Transgressions (pages 671-700): Mahalia S. Desruisseaux, Louis M. Weiss, Herbert B. Tanowitz, Adam Mott and Danny A. MilnerChapter 28 The Blood Retinal Interface: Similarities and Contrasts with the Blood?Brain Interface (pages 701-724): Tailoi Chan?Ling

Free Download Azza Basiouni, "Breaking Barriers with Generative Intelligence. Using GI to Improve Human Education and Well-Being: First International "
English | ISBN: 3031659953 | 2024 | 256 pages | EPUB, PDF | 14 MB + 11 MB
The book constitutes the proceedings for the First International Conference on Breaking Barriers with Generative Intelligence, BBGI 2024, held in Thessaloniki, Greece, on June 10, 2024. This Workshop is part of the 20th International Conference on Intelligent Tutoring Systems (ITS2024) which was held in Thessaloniki, from June 10 to June 13, 2024.

Free Download Maria Jose Alonso, Noemi S. Csaba, "Nanostructured Biomaterials for Overcoming Biological Barriers"
English | 2012 | ISBN: 1849733635 | PDF | pages: 643 | 172.6 mb
This book provides a critical overview of the advances being made towards overcoming biological barriers through the contribution of nanosciences and nanotechnologies. Overcoming these barriers is of primary importance for solving the problems of many current drugs and vaccines and it is also especially relevant for the commercial exploitation of new therapeutic strategies i.e. gene and cellular therapies. Despite important information that has been covered in recently published books related to nanomedicine (mainly oriented to technologies and applications), there is still an important gap related to the relationship between the chemical properties of nanobiomaterials and their interaction with the biological environment. Thus, this comprehensive new book that is presented with a clear and organised structure dedicated to the different biological barriers relevant for drug delivery applications will focus on (i) mechanistic issues related to the interaction between drug delivery systems and biological barriers and (ii) the analysis of the critical factors determining the efficacy of nanobiomaterials for specific applications. Moreover, this field has become highly multidisciplinary over the last decade, leading to the development of new products, as well as to significant advances from the regulatory point of view. Moreover, this book will also provide an up-to-date view on the clinical relevance of nanomedicine and on its possible impact on global health.

Free Download The Vindication of the Big Bang: Breakthroughs and Barriers by Barry Parker
English | PDF | 1993 | 348 Pages | ISBN : 0306444690 | 25.9 MB
About a year and a half ago a colleague from a nearby university came to ISU to give a talk. His topic was "Why the Big Bang Theory Is Wrong." During his talk he listed the tests that a good cosmology should be able to pass, and he attempted to show that other theories passed the tests just as well as the big bang theory did. He was quite emphatic in his assertion that the big bang theory was no better than certain other theories.

Free Download Eradicating Energy Poverty: Overcoming ‘Barriers’ to Decentralized Energy Systems in India
by Manashvi Kumar Singh
English | 2022 | ISBN: 9811670722 | 474 Pages | True PDF | 37 MB

Free Download The Gender Bias: The Barriers That Hold Women Back, and How to Break Them
by Dr. Sabrina Cohen-Hatton
English | 2023 | ISBN: 1788707877 | 282 Pages | True ePUB | 0.4 MB