Tag: Cardiovascular

Free Download Handbook of Cardiovascular Research By Jorgen Brataas, Viggo Nanstveit
2009 | 484 Pages | ISBN: 1607417928 | PDF | 6 MB
Cardiovascular disease refers to the class of diseases that involve the heart of blood vessel. Most countries face high and increasing rates of cardiovascular disease. Each year, heart disease kills more Americans than cancer. It is the number one cause of death and disability in the U.S. and most European countries. The causes, prevention and/or treatment of all forms of cardiovascular disease are active fields of biomedical research. This book presents current research from around the world in this field.

Free Download Cardiovascular Genomics By Bruno Baudin (auth.), Mohan K. Rai ADA PhD, Julian F. R. Paton PhD, Sergey Kasparov MD, PhD, Michael J. Katovich PhD (eds.)
2005 | 362 Pages | ISBN: 1588294005 | PDF | 6 MB
After more than 50 years of limited success in controlling blood pressure with traditional antihypertensive drugs, the time is ripe to explore alternate strategies for managing cardiovascular diseases. In Cardiovascular Genomics, recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. They involve genetic linkage analysis and substitution mapping using congenic strains, microarray techniques, and strategies for discovery in animal models of hypertension. The new transgenic mouse models that either over- or underexpress angiotensinogen are used to illuminate the function of the tissue renin-angiotensin systems, enhancing the understanding of the role of polymorphisms, a crucial factor for effective design of new drugs. The chapters on gene transfer and gene therapy cover a wide variety of topics ranging from novel clinical applications for treating stroke, coronary, and peripheral vascular diseases, to producing new cardiovascular cells and tissues, to using viral vectors as tools. A value-added compact disk containing a companion ebook version of Cardiovascular Genomics is included for downloading and use in the reader’s PC or PDA. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both cutting-edge scientific approaches through the new science of cardiovascular genomics, and the efficacious results it is now possible to obtain.

Free Download Oxidative Stress in Cardiovascular-Metabolic Diseases
English | 2024 | ISBN: 3031621301 | 310 Pages | PDF EPUB (True) | 31 MB
The book dissects the role of oxidative stress in the pathogenesis of the leading causes of global morbidity and mortality, i.e. cardiovascular and metabolic diseases. The chapters discuss topics related to the role reactive oxygen species (ROS) play in hypertension, atherosclerosis, diabetes, obesity and related pathologies. One chapter discusses the clinical efficacy and safety considerations of GLP-1 receptor agonists and SGLT-2 inhibitors in obesity management and the associated cardiovascular complications. Another chapter discusses the context-dependent roles of matrix metalloproteases, and how their activity can be modulated and utilized for the development of improved drugs for cardiometabolic diseases. Moreover, how ROS and aging interplay to precipitate cardiovasculo-metabolic disease is discussed and highlighted. Similarly, how sex and sepsis interplay in the context of cardiorenal disease is teased out in one of the chapters. Preventive measures that can abrogate ROS-induced cardiovasclo-metabolic disease are discussed and clarified in the hope of reducing such a debilitating battery of diseases. Another chapter is fully dedicated to the roles of ROS in atherosclerosis, while another chapter deals with mechanisms and effect of ROS on various phenotypes of adipose tissues in the context of cardiovasculo-metabolic disease. A chapter also discusses the link between traumatic brain injury (TBI) and cardiovascular impairments, and how ROS plays a significant role in TBI-induced cardiovascular disease. A section dedicated to antioxidants as potential therapy is also included. Given the complexity of the mechanisms implicated in ROS-modulated responses, it remains challenging to assert a conclusive argument and pre-determined regimen for incorporating antioxidants into conventional therapies. In all of the chapters, the molecular, cellular, genetic, and pharmacological mechanisms implicated are covered from an applied science perspective.

Free Download I.W. Fong, "Infections and the Cardiovascular System: New Perspectives"
English | 2003 | pages: 275 | ISBN: 1475777868, 0306474042 | PDF | 10,2 mb
Infectious agents have been recognized to involve the heart and vascular system for well over a century. Traditional concepts and teachings of their involvement in the pathogenesis of disease have been by a few established mechanisms. Since the last decade of the 20th century there has been renewed interest in the medical and public media on infectious diseases affecting the cardiovascular and cerebrovascular systems, through their relationship with the development of acceleration of atherosclerosis. This volume highlights and reviews new perspectives of infections on the cardiovascular system as never before. It is a truly valuable resource for scientists, researchers, residents, and fellows in the fields of infectious disease, cardiology, and microbiology.

Free Download Stephen M. M. Factor, Maria A. Lamberti-Abadi, Jacobo Abadi, "Handbook of Pathology and Pathophysiology of Cardiovascular Disease"
English | 2002 | pages: 310 | ISBN: 147578368X, 0792375424 | PDF | 25,4 mb
Autopsy derives from the greek word autopsia, which means act of seeing with one’s own eyes. It remains the most objective and accurate method to understand human. disease. Unfortunately, the volume of autopsies in teaching hospitals has decreased dramatically over the past years. The crucial factors that account for this are the recent progress and development of new technologies, especially in diagnostic imaging, immunology, cell biology and genetics. Additionally, the perpetual fear of legal liability by physicians accounts for its further decline. Consequently, physicians and medical students are engaged in fewer autopsies and are not reaping the rich educational rewards that accompany these examinations. The purpose of the autopsy is not only to establish the cause of death, but also to determine the nature and course of the disease process. Our goal with this book is to emphasize the importance of the post-mortem exam and the correlation between pathologic material and clinical data by analyzing actual cases with problem-based methodology. The focus of this handbook is on cardiovascular disease, and when appropriate, other disease categories are included if they have an impact on cardiovascular function. The approach is more than the usual clinico-pathological correlation. Rather, we attempt to present the material from the perspective of the autopsy table. We use the clinical data as the initial framework and the autopsy findings to develop a true understanding of the disease and the associated pathophysiology of the condition.

Free Download Cardiovascular Considerations in Hematopoietic Stem Cell Transplantation
English | 2024 | ISBN: 3031536584 | 297 Pages | PDF EPUB (True) | 35 MB
This book discusses the epidemiology and the known cardiotoxic effects of chemoradiation agents in addition to newer therapies in hematopoietic stem cell transplantation (HSCT). Recent expert consensus statements from cardiology and hematology/oncology societies are reviewed in regard to risk stratification of the patient based on the type of treatments they are undergoing. Finally, gaps in knowledge are identified with proposed avenues of research that allow for more accurate risk assessment, prediction and potential treatment of the HSCT patient in attenuating the risk of developing cardiovascular comorbidities.

Free Download Application of Biomaterials in the Treatment of Cardiovascular Diseases
English | 2024 | ISBN: 9811977119 | 439 Pages | PDF EPUB (True) | 72 MB
This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

Free Download Application of Biomaterials in the Treatment of Cardiovascular Diseases
English | 2024 | ISBN: 9811977119 | 439 Pages | PDF EPUB (True) | 72 MB
This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

Free Download Pathophysiology of Heart Disease: An Introduction to Cardiovascular Medicine, 7th Edition
by Leonard S. Lilly
English | 2020 | ISBN: 1975120590 | 512 Pages | True PDF | 25 MB

Free Download Dr Tommy Mitchell, "Wonders of the Human Body: Cardiovascular & Respiratory Systems "
English | ISBN: 0890519285 | 2016 | 106 pages | PDF | 42 MB
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