Tag: Chromatography

Process Gas Chromatography Advanced Design and Troubleshooting


Free Download Process Gas Chromatography: Advanced Design and Troubleshooting
English | 2025 | ISBN: 1119791472 | 458 Pages | PDF, EPUB (True) | 30 MB
Process gas chromatography is a method used to separate and analyze chemical compounds in an industrial process. First established in the middle of the twentieth century, it aims to return analytical results rapidly enough that they can be used to optimized a fluid processing plant. It is a complex process which demands meticulous training of process gas chromatograph engineers and operators.

(more…)

Basic of Chromatography and HPLC


Free Download Basic of Chromatography and HPLC by Arunadevi S Birajdar
English | August 1, 2023 | ISBN: 9395039086 | 134 pages | EPUB | 6.20 Mb
Present book is written with a view to help undergraduate and postgraduate students learn the fundamental principles and applications of different types of chromatography. The author aim to facilitate the understanding of chromatographic techniques, and in detail about HPLC Techniques, Instrumentation with steps involved in New method development process through description of techniques in a simple manner.

(more…)

Applications of Ion Chromatography for Pharmaceutical and Biological Products


Free Download Applications of Ion Chromatography for Pharmaceutical and Biological Products By
2012 | 455 Pages | ISBN: 0470467096 | PDF | 5 MB
This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.Content: Chapter 1 Ion Chromatography-Principles and Applications (pages 1-21): Lokesh BhattacharyyaChapter 2 Retention Processes in Ion?Exclusion Chromatography: A New Perspective (pages 23-47): Milko Novic and Paul R. HaddadChapter 3 Pulsed Electrochemical Detection in Ion Chromatography (pages 49-90): William R. LacourseChapter 4 Suppressor Design and Detection for Ion Chromatography (pages 91-105): Kannan Srinivasan, Sheetal Bhardwaj, Rong Lin and Christopher PohlChapter 5 Modelling and Optimization of Ion Chromatographic Separations of Pharmaceutically Relevant Organic Ions (pages 107-133): Philip Zakaria, Greg Dicinoski, Melissa Hanna?Brown and Paul R. HaddadChapter 6 Ion Chromatography in Pharmaceutical Drug Analysis (pages 135-157): Lokesh BhattacharyyaChapter 7 Analysis for Impurities by Ion Chromatography (pages 159-174): Shreekant V. KarmarkarChapter 8 Ion Chromatography Analysis of Aminoglycoside Antibiotics (pages 175-192): Valoran P. Hanko and Jeffrey S. RohrerChapter 9 Use of Cation?Exchange Ion Chromatography in the Analysis of Pharmaceuticals (pages 193-220): Christopher Pohl, Maria Rey and Rosanne SlingsbyChapter 11 High Performance Ion Chromatographic Analysis of Cholinergic Compounds: Carbachol and Bethanechol, and Associated Degradation Products (pages 237-245): David TrowbridgeChapter 12 Ion Chromatographic Analysis of Pharmaceuticals for Authenticity and Adulteration (pages 247-257): David S. JacksonChapter 13 Ion Chromatography of Drug Product Counter?Ions and other Ions in Drug Products (pages 259-269): Brian M. De Borba and Jeffrey S. RohrerChapter 14 Sample Preparation Techniques in Ion Chromatography for Pharmaceutical Applications (pages 271-283): Jay GandhiChapter 15 Validation of Ion Chromatographic Methods (pages 285-308): Shreekant V. KarmarkarChapter 16 Pharmacopeial Applications of Ion Chromatography (pages 309-320): Ravi RavichandranChapter 10 Comprehensive Approaches for Measurement of Active Pharmaceutical Ingredients, Counter?Ions, and Excipients Using HPLC with Charged Aerosol Detection (pages 221-236): Christopher Crafts, Bruce Bailey, Paul Gamache, Xiaodong Liu and Ian AcworthChapter 17 Glycan Analysis by High Performance Anion Exchange Chromatography with Pulsed Amperometric Detection (pages 321-338): Lokesh BhattacharyyaChapter 18 Monosaccharide Analysis of Glycoproteins by High?Performance Anion?Exchange Chromatography with Pulsed Amperometric Detection (pages 339-350): Jeffrey S. RohrerChapter 19 Two?Dimensional Ion Chromatography for Simultaneous Determination of Amino Acids and Carbohydrates (pages 351-364): Petr Jandik and Jun ChengChapter 20 Monitoring Protein N?Glycosylation Consistency Using HPAEC?PAD (pages 365-377): Carl GreyChapter 21 Oligosaccharide Analysis by High?Performance Anion?Exchange Chromatography Hyphenated to Integrated Pulsed Amperometric Detection and On?Line Ion?Trap Mass Spectrometry (pages 379-391): Cees BrugginkChapter 22 Applications of Ion Chromatography in Biological Product Analyses (pages 393-421): Alfred V. Del Grosso and Brandon DuongChapter 23 High Performance Anion?Exchange Chromatography with Pulsed Amperometric Detection (HPAEC?PAD) Analysis of GBS Glycoconjugate Vaccines: From Fermentation to Final Product (pages 423-434): Stefano Ricci, Barbara Fabbri, Sara Giannini, Silvia Bernardini, Marcello Morelli and Sandro D’AscenziChapter 24 Stability Studies and Characterization of Meningococcal A, C, Y, and W135 Glycoconjugate Vaccine (pages 435-447): Valeria Carinci, Alberto Bernardini, Cristiana Campa, Claudia Magagnoli, Francesca Beccai and Sandro D’Ascenzi

(more…)

Applied Thin-Layer Chromatography Best Practice and Avoidance of Mistakes, Second Edition


Free Download Applied Thin-Layer Chromatography: Best Practice and Avoidance of Mistakes, Second Edition By Elke Hahn?Deinstrop(auth.)
2006 | 320 Pages | ISBN: 3527315535 | PDF | 5 MB
Thin-layer chromatography (TLC) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This new edition of the practical TLC guide features a completely revised chapter on documentation, now including the use of digital cameras. Selected new sorbents and instruments are also introduced. Why has the prior edition been successful? All steps of the analytical procedure are clearly explained, starting with the choice of a suitable TLC technique and ending with data evaluation and documentation. Special emphasis is put on the proper choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering e. g. precoated layers, solvents and developing chambers, including information on suppliers. Many practical hints for trouble shooting are given. All this is illustrated with numerous coloured figures. How to use TLC in compliance with GLP/GMP regulations is described in detail, including the required documentation. Therefore the reader can very easily compile his own standard operating procedures.Content: Chapter 1 Introduction (pages 1-13): Chapter 2 Precoated Layers (pages 15-33): Chapter 3 Before the TLC Development Process (pages 35-68): Chapter 4 Solvent Systems, Developing Chambers and Development (pages 69-112): Chapter 5 Evaluation Without Derivatization (pages 113-123): Chapter 6 Derivatization (pages 125-151): Chapter 7 Evaluation After Derivatization (pages 153-180): Chapter 8 Documentation (pages 181-201): Chapter 9 GMP/GLP?Conforming Operations in TLC (pages 203-239): Chapter 10 Effects of Stress (pages 241-245): Chapter 11 Special Methods in TLC (pages 247-252): Chapter 12 Appendix (pages 253-270):

(more…)

Microbore Column Chromatography A Unified Approach to Chromatography


Free Download F. J. Yang, "Microbore Column Chromatography: A Unified Approach to Chromatography"
English | 1988 | pages: 420 | ISBN: 0824779894, 0367451271 | PDF | 28,5 mb
This book describes the various aspects of microbore column chromatography. It provides readers with an in-depth understanding of the supercritical fluid chromatography and microbore high-performance liquid chromatography.

(more…)

High-Performance Liquid Chromatography of Peptides and Proteins Separation, Analysis, and Conformation


Free Download Colin T. Mant, Robert S. Hodges, "High-Performance Liquid Chromatography of Peptides and Proteins: Separation, Analysis, and Conformation"
English | 1991 | ISBN: 084936549X, 0367402963 | PDF | pages: 961 | 51.9 mb
This book consists of a series of 82 precise, easy-to-read articles by internationally renowned scientists and emphasizes the practical approach to HPLC with minimal theory, although the underlying principles for peptide and protein separations are clearly expressed. All of the major modes of microbore, ultrafast and analytical HPLC are discussed, including size-exclusion, ion-exchange, reversed-phase, hydrophobic interaction, and affinity and immunoaffinity chromatography. A section on preparative HPLC, including displacement techniques, is also presented. Problem-solving approaches to the separation of various classes of biologically active peptides and proteins are thoroughly explored, while the importance of peptide standards for monitoring column performance and for optimizing separation conditions is emphasized. Several articles focus on the choice of the correct detection method (electrochemical, UV, fluorescence), as well as the need for a proper knowledge of approaches to column and instrument maintenance and trouble-shooting. A section on predictive approaches deals with both computer simulation of peptide separations and peptide structure. The book also includes complementary techniques to HPLC, as well as other useful applications of HPLC. It enables both novice and experienced chromatographers to realize the full potential of this extremely powerful technique, in the process making an important contribution to scientific literature.

(more…)