Tag: Drug

Free Download Ethan G. Verrite, "Drug Resistant Neoplasms "
English | ISBN: 1607412551 | 2009 | 254 pages | PDF | 11 MB
"One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumors, even those from the same tissue of origin. Frequently, resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anticancer drugs from cells. Studies on the mechanisms of cancer drug resistance have yielded important information about how to circumvent this resistance to improve cancer chemotherapy and its implications forpharmacokinetics of many commonly used drugs. This book presents new and important research in this field."-✅Publisher‘s description.

Free Download Polypharmacology: Strategies for Multi-Target Drug Discovery
English | 2025 | ISBN: 139418283X | 482 Pages | PDF | 19 MB
Polypharmacology covers the two-sided nature of polypharmacology: its relevance for adverse drug effects, as well as its benefit for certain therapeutic drug classes in effectively treating complex diseases like psychosis and cancer. The book provides practical guidelines and advice to help readers design drugs that have multiple targets while minimizing unwanted off-target effects, discusses important disease areas like viral infection, diabetes, and obesity that have advanced significantly in the last decade, and guides researchers in neighboring areas to polypharmacology.

Free Download Walter A. Korfmacher, "Using Mass Spectrometry for Drug Metabolism Studies"
English | 2004 | pages: 363 | ISBN: 0849319633 | PDF | 10,0 mb
Mass spectrometry (MS) is fast becoming the premier tool for analyzing various drug metabolism samples in the early phases of drug discovery and research. Introducing the newer, more powerful MS equipment and exploring new applications for using them, this book provides a state-of-the-art look at this promising field.

Free Download Methods in Neurodegenerative Disease Drug Discovery
English | 2025 | ISBN: 1071642316 | 368 Pages | PDF (True) | 20 MB
This book explores the latest developments in the identification of biomarkers for early diagnosis of neurodegenerative diseases and methodologies for the biophysical; in vitro; cell-based; and in vivo profiling, during the early phases of drug discovery, new hits, leads, and drug candidates directed to a variety of biological targets with key pathogenic roles in neurodegenerative diseases. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Free Download Modern CNS Drug Discovery:
Novel Therapeutics for Psychiatric and Neurological Diseases: From Target Identification to Regulatory Approval
English | 2024 | ISBN: 3031619919 | 464 Pages | PDF EPUB (True) | 54 MB

Free Download Maria A. Popescu, "Drug Delivery "
English | ISBN: 1613245386 | 2011 | 222 pages | PDF | 4 MB
In drug delivery, active pharmaceutical ingredient (API) is delivered to the patient through different methods and shapes which are called pharmaceutical dosage forms. Each API has specific physicochemical and pharmaceutical properties which require a suitable pharmaceutical dosage form to be delivered to the body. In this book, the authors present current research from across the globe in the study of drug delivery. Topics discussed include pharmaceutical dosage forms; drug delivery through multifunctional polymeric nanoparticles; targeted liposomal based chemotherapies; the stability of drug delivery PLGA nanoparticles; and, the influence of particle physicochemical properties on delivery of drugs by dry powder inhalers to the lung.

Free Download R.N. Karch, Amy M., "Lippincott Nursing Drug Guide"
English | ISBN: 1469839377 | 2015 | 1515 pages | EPUB | 34 MB
A comprehensive, up-to-date drug guide for nursing students and practicing nurses, Lippincott Nursing Drug Guide provides quick A-to-Z access to current, vital drug information. The book provides complete monographs for 725 common drugs, including generic and trade names, pronunciations, pregnancy risk category, controlled substance schedule (if appropriate), drug classes, therapeutic actions, indications, contraindications and cautions, available forms, dosages, pharmacokinetics, IV facts (if appropriate), adverse effects, interactions, and nursing considerations organized by nursing process steps (assessment, interventions, and teaching points).

Free Download Drug and Therapy Development for Triple Negative Breast Cancer by Pravin Kendrekar, Vinayak Adimule, Tara Hurst
English | June 12, 2023 | ISBN: 3527351752 | 320 pages | MOBI | 5.06 Mb
Drug and Therapy Development for Triple Negative Breast Cancer

Free Download Open Access Databases and Datasets for Drug Discovery (Methods & Principles in Medicinal Chemistry) by Antoine Daina, Michael Przewosny, Vincent Zoete
English | October 2, 2023 | ISBN: 3527348395 | 352 pages | MOBI | 17 Mb
Open Access Databases and Datasets for Drug Discovery

Free Download Gianpietro Sechi, "Drug Related Encephalopathies"
English | ISBN: 1604567457 | 2008 | 508 pages | PDF | 7 MB
This book is the first comprehensive reference to the relationship between a myriad of drugs commonly used in neurology, psychiatry and internal medicine, and the occurrence of acute or sub-acute encephalopathy. In 12 chapters, highly-skilled, well-known experts in the field discuss the determinants, natural courses, genetics, pathophysiology and treatment of most of the drug related encephalopathies which have relevance in clinical practice. This text provides new insights on the use of drugs and is an essential source of assistance for neurologists, psychiatrists, neurosurgeons, other clinicians and trainees at all levels who treat neurological patients.