Tag: Drug

Novel Drug Delivery Systems in the Management of Chronic Diseases


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English | 2025 | ISBN: 1774915863 | 430 Pages | PDF (True) | 13 MB
This new volume covers recent trends of NDDS in the management of the most frequently occurring chronic diseases. The authors outline the different materials that can help prepare NDDS with desired properties. The book looks at NDDS applications for central nervous system (CNS) diseases, including Alzheimer’s and Parkinson’s as well as for HIV, cancer diabetes, asthma and respiratory complications, and diabetic retinopathy. Chapters also look at the use of NDDS in herbal drug delivery, the involvement of artificial intelligence in development of NDDS, and more.

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Drug Repurposing


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English | 2024 | ISBN: 9819750156 | 472 Pages | PDF EPUB (True) | 22 MB
This book offers an insightful exploration of drug repurposing, an innovative approach to drug discovery and development that has the potential to revolutionize the field of medicine. It begins with an introduction to drug repurposing and its history, providing a comprehensive overview of the subject. The readers will embark on a journey through the diverse landscape of drug repurposing strategies. From in silico methods of predicting drug-disease associations to experimental approaches to the integrations of artificial intelligence (AI) and machine learning (ML) in drug repurposing for validating repurposed candidates. The book also delves into the application of drug repurposing in various disease areas, including cancer, inflammatory disorders, and CNS disorders. It explores the potential hurdles involved in the regulatory aspects of the process. The book further covers drug products under clinical trials and provides an overview of the future perspectives of drug repurposing. With its detailed and informative content, this book is a must-read for researchers, clinicians, and healthcare professionals interested in the exciting field of drug repurposing.

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Chemistry and Pharmacology of Drug Discovery


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English | 2024 | ISBN: 1394225121 | 418 Pages | PDF | 29 MB
Chemistry and Pharmacology of Drug Discovery illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines, discussing a total of 20 drugs that are all FDA-approved post 2021―some of which are first-in-class and revolutionary.

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Principles and Practice of Pharmacovigilance and Drug Safety


Free Download Principles and Practice of Pharmacovigilance and Drug Safety by Jimmy Jose, Anthony R. Cox, Vibhu Paudyal
English | PDF EPUB (True) | 2024 | 557 Pages | ISBN : 3031510887 | 46.9 MB
The science of drug safety and pharmacovigilance has rapidly evolved in the 21st century. The knowledge and principles it contains are of increasing importance in clinical and practice settings. The aim of this book is to deal with the gap in knowledge about pharmacovigilance and drug safety, including the application of pharmacovigilance knowledge to individual patient cases in clinical practice.

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Modeling, Control and Drug Development for COVID-19 Outbreak Prevention


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English | EPUB | 2022 | 1115 Pages | ISBN : 3030728331 | 159.6 MB
This book is well-structured book which consists of 31 full chapters. The book chapters’ deal with the recent research problems in the areas of modeling, control and drug development, and it presents various techniques of COVID-19 outbreak prevention modeling. The book also concentrates on computational simulations that may help speed up the development of drugs to counter the novel coronavirus responsible for COVID-19.

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Ethnomedicinal Plants for Drug Discovery Current Developments


Free Download Ethnomedicinal Plants for Drug Discovery: Current Developments by Akhileshwar Kumar Srivastava, Ramesh Kumar Ahirwar, Deepanker Yadav, D. Guru Kumar
English | PDF EPUB (True) | 2024 | 560 Pages | ISBN : 9819734045 | 64 MB
This book explains the translational aspects of ethnomedicinal plants of different geographical regions including India by explaining the medicinal properties against several diseases, genomic evolution in changing environments, metabolic profiling for biomarker discovery, the role of non-coding RNA in the synthesis of secondary metabolites, genome-wide transcriptome profiling, application of pluripotent stem cells for drug discovery, the importance of high-throughput omics, and genome-editing techniques. In addition, some of the chapters have been designed to describe the role of artificial intelligence, plant database, and network-based drug discovery to explore the medicinal importance of compounds as well as challenges and opportunities in drug discovery from ethnomedicinal plants. The book serves as a great source of information for the students, researchers/scientists of diverse fields such as pharmacognosy, plant physiologists, biotechnologists, and pharmaceutical scientists etc., working in the areas of phytotherapy from ethnomedicinal plants.

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Drug Targets for Plasmodium Falciparum Historic to Future Perspectives


Free Download Drug Targets for Plasmodium Falciparum: Historic to Future Perspectives by Mohammed Tarique
English | PDF EPUB (True) | 2024 | 205 Pages | ISBN : 9811944830 | 59.5 MB
This book offers a comprehensive exploration of malaria, a life-threatening disease affecting millions globally, with a focus on the parasitic organisms of the genus Plasmodium that cause it. It discusses the challenges posed by the disease, especially in economically developing regions, and delves into the biology and pathophysiology of the Plasmodium species, including their genetic flexibility and resistance to treatments. Special attention is given to P. falciparum, the most dangerous of these parasites, detailing its complex life cycle, interaction with human hosts, and the severe clinical manifestations it can induce. The book further explores the global health concern of antimalarial drug resistance, highlighting the WHO’s efforts in combating the disease and the necessity for novel treatments. Innovative research directions, such as targeting the unique organelles of Plasmodium like the apicoplast and employing proteasome inhibitors, are thoroughly examined as potential strategies in the development of new antimalarial drugs. Additionally, it addresses the critical role of the hemoglobin digestion process in the parasite’s lifecycle, presenting it as a promising target for therapeutic intervention. This work is an essential resource for researchers, clinicians, and policymakers involved in malaria control and drug development, providing insights into the current challenges and future directions in the fight against this endemic disease.

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Drug Allergy Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships


Free Download Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships by Brian A. Baldo
English | EPUB | 2021 | 742 Pages | ISBN : 303051739X | 98 MB
The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships.

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Advances in Antifungal Drug Development Natural Products with Antifungal Potential


Free Download Advances in Antifungal Drug Development :Natural Products with Antifungal Potential by Nikhat Manzoor
English | PDF EPUB (True) | 2024 | 723 Pages | ISBN : 9819751640 | 86.2 MB
This book explores the antifungal properties of natural products and reviews their antifungal mechanism. An introductory chapter illustrates the various fungal pathogenic species, common fungal diseases, and general mechanisms of action of various antifungal classes, including natural products. The book comprises seven sections and each section contains chapters on the efficacy and antifungal mode of action of plant extracts, essential oils, natural compounds, their derivatives, and plant-based nanoparticles. A section summarizes the antifungal efficacy of compounds derived from sources other than plants, like microbes. Besides compound toxicity, the book explores the antifungal mode of action and efficacy against the virulence and pathogenicity of fungal pathogens like Candida, Aspergillus, Cryptococcus, Histoplasma, and other pathogenic fungi. Further, the book also describes recent advancements in the discovery of novel drug targets and therapeutic strategies that are non-toxic and more efficacious for combating drug resistance. This book is an invaluable source for researchers working in the field of fungal biochemistry, anti-microbial, and anti-bacterial and undergraduate and postgraduate students of microbiology and pharmacology.

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