Tag: Endogenous

Free Download Pharmacology of Endogenous Neurotoxins: A Handbook By Toshimitsu Niwa, Mitsuharu Kajita, Toshiharu Nagatsu (auth.), Andreas Moser (eds.)
1998 | 273 Pages | ISBN: 1461273757 | PDF | 12 MB
It is a great pleasure to write the foreword to this important volume for several reasons. First: As far as we know, already primitive societies had to cope with environmental toxins of many kinds and set up regulations to limit their effects on food and drug use. Modem science, synthesizing tens of millions of new compounds has incredibly magnified this challenge. Today, xenobiotic metabolism has become a crucial task for humans and many other species alike. Second: When reading this book, one is impressed by the extraordinary speed at which neurotoxicology has advanced. Obviously, processing (and endogenous formation) oftox ins has become an extremely relevant topic. When I had the chance, almost three decades ago, to work in chemical pharmacology with Bernard B. Brodie at NIH, the drug metabo lizing system of the liver had just been recognized and characterized. We had just started to work on the biogenic amines, newly discovered cyclic nucleotides in rat brain, human cere brospinal fluid, and on the effects of toxic drugs like amphetamines. Today, biochemical neuropharmacology is a mature field of neuroscience.

Free Download Endogenous Opioids: From Basic Science to Biopsychosocial Applications by Patrick L. Kerr, Cristian Sirbu, John M. Gregg
English | PDF EPUB (True) | 2024 | 456 Pages | ISBN : 3031454928 | 56.7 MB
This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus. Topics covered range from basic scientific investigations, to clinical applications, to investigations in areas such as oncology, childbirth, and disordered eating, to psychosocial contexts such as volunteering and positive emotions. One of the main goals of Endogenous Opioids is to provide recommendations for new directions in medical research and health policy that are rooted in sound scientific research.

Free Download Yoshiaki Nishikawa, "Seeds for Diversity and Inclusion: Agroecology and Endogenous Development"
English | ISBN: 3030894045 | 2022 | 218 pages | PDF | 3 MB
This open access book will contribute to a more nuanced debate around seed system resilience that goes beyond the dominant dichotomous conceptualization of seed governance often characterized as traditional vs modern, subsistence vs commercial, or local vs global. While reflecting on the expanding oligopoly in the current seed system, the authors argue that such classifications limit our ability to critically reflect on and acknowledge the diverse approaches through which seed governance is practiced around the world, at various scales, creating a mosaic of dynamic complementarities and autonomies. The authors also highlight the importance of this much needed dialogue through case studies of seed governance approaches and practices found in and around Japan.