Tag: Factors

Free Download FOXO Transcription Factors
English | 2025 | ISBN: 1071642162 | 201 Pages | PDF (True) | 14 MB
This second edition volume expands on the previous edition with updates on the latest techniques and technologies used in FOXO research. The chapters in this book are organized into five parts. Part One covers biochemical techniques used to analyze phosphorylation status of FOXO proteins, identify FOXO binding partners, and assess FOXO-specific transcriptional activity. Part Two highlights genetic techniques that are used to identify functional domains and validate disease relevance. Part Three talks about biophysical and bioinformatic methods to study the structure and dynamics of FOXO proteins, and protein-protein interactions. Part Four discusses different fluorescence and imaging techniques to measure FOXO translocation, and Part Five focuses on functional studies in model organisms to characterize cell death regulation and life- and healthspan. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Free Download Natalie Chambers, "Binge Eating: Psychological Factors, Symptoms and Treatment"
English | ISBN: 1606922424 | 2009 | 284 pages | PDF | 4 MB
Binge eating disorder (BED) is the most common eating disorder among men and women. This book centres on binge eating, which consists of episodes of uncontrollable overeating, followed by compensatory behaviour (ie: purging, fasting, heavy exercising). People who suffer from this disease often try to hide their binge-eating episodes from others, and often feel ashamed or depressed about their overeating. Many factors may contribute to binge-eating, such as dissociation, which may undermine an individual’s body image, and impulsivity. This book focuses on such factors as well as the frequency with which such behaviours occur in multi-ethnic populations, and the differences in frequency rates as a function of gender and identity. The differences in binge eating and bulimia nervosa behaviours are also explained, as well as the theory that binging on some palatable foods, such as sugar, can result in addictive-like behaviour. The association between emotional abuse in childhood and future binge eating episodes are explained as well as the prevalence of BE episodes in overweight or obese children or adolescents. The effectiveness of certain treatments for binge-eating are described, including cognitive behavioural therapy (CBT), motivational enhancement therapy (MET) and combined treatment.

Free Download James Dobbins Former Special Envoy for Afghanistan Kosovo Bosnia Haiti and Somalia, "Overcoming Obstacles to Peace: Local Factors in Natin-Building"
English | ISBN: 0833078607 | 2013 | 348 pages | EPUB | 10 MB
Following on a series of RAND Corporation studies of nation-building, this monograph analyzes the impediments that local conditions pose to successful outcomes in these interventions. It examines how external actors and local leaders in a variety of societies modified or worked around those conditions to promote enduring peace.

Free Download Alejandro Romero Pena, "Osteoporosis: Risk Factors, Symptoms and Management "
English | ISBN: 162081210X | 2012 | 177 pages | PDF | 6 MB
Osteoporosis is a systemic, debilitating disease of the skeleton, characterised by significantly decreased bone mass in combination with the deterioration of bone microarchitecture. This process results in weakened bone with a great propensity for fracture under low-energy stress. This book presents current research in the study of the risk factors, symptoms and management of osteoporosis. Topics include the influence of osteoporosis in oral health; assessment of risk fracture risk and therapeutic effects on osteoporosis; diagnosing future bone fracture; genetic and environmental factors in human osteoporosis; the pathogenesis of skeletal complications in patients with endogenous hypercorticism; genetic and postmenopausal osteoporosis risk; and severely suppressed bone turnover associated with bisphosphonate for osteoporosis.

Free Download Salvatore De Rossi, "Aneuploidy: Etiology, Disorders and Risk Factors "
English | ISBN: 1621000702 | 2012 | 171 pages | PDF | 5 MB
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Free Download Bethany R. Collier, "Handbook on Ovarian Cancer: Risk Factors, Therapies and Prognosis "
English | ISBN: 1634838742 | 2015 | 247 pages | PDF | 3 MB
Ovarian cancer is the third most diagnosed gynecologic cancer and the first leading cause of death from all of gynecological malignancies. High mortality of the patients is usually associated with the progression of the disease. Most patients are diagnosed within the advanced stages due to lacking relevant diagnostic and screening markers. This handbook discusses several risk factors of ovarian cancer. It also examines the different therapies provided to ovarian cancer patients, and the prognosis of the cancer.

Free Download Dominick Santiago, "Stuttering: Risk Factors, Public Attitudes and Impact on Psychological Well-Being "
English | ISBN: 1634836952 | 2015 | 118 pages | PDF | 13 MB
Stuttering is a communication and fluency disorder usually beginning in childhood. Developmental stuttering (DS) is a speech disorder which is characterised by repetitions, prolongations or pauses that disrupt the normal flow of speech. It occurs in approximately 5-8% of the pres-school children and recovers spontaneously in 70-80% of the cases. The role of a stuttering person’s possible tendency toward psychosocial-emotional disorder as an etiologic cause of stuttering is discussed in this book. Overall, research findings appear to support the role of tendency toward psychosocial-emotional disorder as an important contributing cause in the etiology of developmental stuttering. The authors also examine the psychological impact of stuttering, the neurobiological differences in the cerebrum between persons with developmental stuttering and the public attitudes towards people who stutter.

Free Download Navigating Career Transitions: Key Factors for a Successful Job Move by bright days
English | October 30, 2024 | ISBN: N/A | ASIN: B0DLK95R34 | 122 pages | EPUB | 0.94 Mb
Defining career transitions involves understanding the multifaceted nature of moving from one job to another. This process is not merely about changing positions; it encompasses a thorough evaluation of various factors that can significantly impact both professional and personal lives. For professional adults contemplating a job change, it is crucial to consider aspects such as salary and compensation, work-life balance, and company culture. Each of these elements plays a pivotal role in determining whether a new opportunity aligns with one’s career goals and personal values.

Free Download Christopher J. Denman, "Individual and Contextual Factors in the English Language Classroom: Theoretical, Pedagogical, and Empirical Approaches"
English | 2022 | ISBN: 3030918831 | PDF | pages: 393 | 6.6 mb
This edited volume examines a number of topics related to the roles of individual and contextual factors in English as second or foreign language (ESL/EFL) settings by presenting chapters across the three sections of theoretical and pedagogical approaches, teacher and learner research, and research into the roles of technology. The book has a focus on practical actions and recommendations related to individual and contextual factors in ESL/EFL, with a specific concern with issues of cognition, metacognition, emotion, and identity, and offers perspectives from a diverse range of international education settings. For teachers of ESL/EFL, the effective recognition and integration of individual and contextual factors into the classroom may represent a significant challenge. This is often the case in those settings where native English speaking teachers work in foreign language contexts where they may have limited understanding of local cultures and languages, or where language instructors have class groups that are culturally and linguistically diverse. In these, and similar, contexts, the types and extent of individual and contextual factors impacting on language learning may challenge both learner and instructor expectations of what an effective and supportive classroom is. While such a situation offers numerous opportunities for learners and teachers to expand their knowledge of themselves and each other, it also presents the possibility for ineffective teaching and learning to occur. It is within this framework that the book presents the latest theoretical, pedagogical, and research perspectives from around the world, thereby providing a resource for all stakeholders with an interest in the roles individual and contextual factors play in the English learning process.

Free Download Critical Success Factors in Biomedical Research and Pharmaceutical Innovation: The joint impact of management control and contingencies on performance and effectiveness in research laboratories in medical faculties, health research institutes and inn By S. W. F. Omta (auth.)
1995 | 294 Pages | ISBN: 9401040486 | PDF | 8 MB
Is talent the only key to scientific success? In fact, the answer is: `No’. Management and organisation do make a real, significant difference between success and failure in science. This book presents a clear survey of the critical success factors in biomedical research laboratories. Based on an international, comparative study of 71 research laboratories in medical faculties, large health research institutes and innovative pharmaceutical companies, ready-to-use guidelines are offered to those who are responsible for the management of research groups. Dr. Omta is biochemist and has played a key role in the development of the EU Biotechnology Network. He has performed the comparative study for this book in the position of Managing Director of the Institute for Research in Extramural Medicine in Amsterdam. The author has recently been appointed as Associate Professor at the Faculty of Management and Organisation at the University of Groningen, the Netherlands. This work is a unique guide for heads, professors, or managers of (biomedical) research laboratories in universities, research institutes and innovative pharmaceutical companies, who are seeking rational tools for increasing the performance and effectiveness of their research groups.