Tag: Genome

The Human Genome Features, Variations and Genetic Disorders


Free Download Akio Matsumoto, "The Human Genome: Features, Variations and Genetic Disorders "
English | ISBN: 1607416956 | 2009 | 327 pages | PDF | 10 MB
The sequencing of the human genome reveals our complete complement of genetic material. The sequenced human genome is one of the most international biomedical research projects ever, which is important in our current often all-too-fractured world. This book defines the function of all "unknown" human genes, delineates the functional and phenotypic significance of human genetic variants in humans, and explores the functions of the vast non-genic regions of the human genome. Human genome sequencing has revealed a great opportunity to deeply investigate the biology and evolution of the sex chromosome pair at a more global level, allowing new frontiers in the genetics research, such as a detailed knowledge of the sequence and the gene content of these chromosomes. This book provides the most current research done in this area.

(more…)

The National Plant Genome Initiative Objectives for 2003-2008


Free Download National Research Council, Division on Earth and Life Studies, "The National Plant Genome Initiative: Objectives for 2003-2008"
English | 2002 | pages: 92 | ISBN: 0309085217 | PDF | 3,7 mb
The National Plant Genome Initiative was launched in 1998 as a long-term project to explore DNA structure and function in plants so that useful properties of plants can be understood, improved, and ultimately harnessed to address national needs, including agriculture, nutrition, energy and waste reduction. Experts in the community were asked to consider how to build on current accomplishments in order to address major questions in plant biology and to make recommendations for objectives for the next five-year phase of the Initiative.

(more…)

Computational Methods for 3D Genome Analysis


Free Download Computational Methods for 3D Genome Analysis
English | 2024 | ISBN: 1071641352 | 455 Pages | PDF (True) | 31 MB
This volume covers the latest methods and analytical approaches used to study the computational analysis of three-dimensional (3D) genome structure. The chapters in this book are organized into six parts. Part One discusses different NGS assays and the regulatory mechanism of 3D genome folding by SMC complexes. Part Two presents analysis workflows for Hi-C and Micro-C in different species, including human, mouse, medaka, yeast, and prokaryotes. Part Three covers methods for chromatin loop detection, sub-compartment detection, and 3D feature visualization. Part Four explores single-cell Hi-C and the cell-to-cell variability of the dynamic 3D structure. Parts Five talks about the analysis of polymer modelling to simulate the dynamic behavior of the 3D genome structure, and Part Six looks at 3D structure analysis using other omics data, including prediction of 3D genome structure from the epigenome, double-strand break-associated structure, and imaging-based 3D analysis using seqFISH. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and tools, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

(more…)

The Persimmon Genome (2024)


Free Download Ryutaro Tao, Zhengrong Luo, "The Persimmon Genome"
English | 2022 | ISBN: 3031055837, 3031055861 | PDF | pages: 183 | 9.6 mb
This book will expound the latest information on the current state of persimmon genomics and transcriptomics, with a particular focus on the latest findings and analysis in relation to the most important agronomic traits. The genus Diospyros contains about 400 species distributed all continents of the globe. Most of Diospyros species are distributed in the tropical and subtropical regions, while cultivated persimmon or simply kaki (Diospyros kaki) originates in East Asia and has been grown in China, Japan and Korea for many years. World production of persimmon has been increasing continuously since 1990s, with China being the most producer. Outside Asia, kaki production has been rapidly increasing in Spain in recent years. Because kaki is mostly hexaploid (2n = 6x =90) and its genome size is quite large with the flow cytometric analysis estimation of about 900 Mb, genetic and molecular studies in persimmon are quite complicated. Diploid close relatives of kaki,D. lotus and D. oleifera have been recently used as model species of kaki. Utilizing these species, molecular basis of several economically molecular basis of important traits such as sexuality and astringency has been studied, giving important information for kaki breeding.

(more…)

The Deeper Genome Why there is more to the human genome than meets the eye


Free Download John Parrington, "The Deeper Genome: Why there is more to the human genome than meets the eye"
English | ISBN: 0199688737 | 2015 | 272 pages | AZW3 | 999 KB
Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn’t turn out that way. For a start, we turned out to have far fewer genes than originally thought – just over 20,000, the same sort of number as a fruit fly or worm. What’s more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated ‘junk’?

(more…)

Plant Genome Engineering Methods and Protocols (Methods in Molecular Biology, 2653)


Free Download Plant Genome Engineering: Methods and Protocols (Methods in Molecular Biology, 2653) by Bing Yang, Wendy Harwood, Qiudeng Que
English | March 31, 2023 | ISBN: 1071631306 | 403 pages | MOBI | 14 Mb
This volume provides readers with a collection of the latest protocols used to study plant genome editing and trait engineering. The chapters in this book are organized into five parts: genome engineering systems; machinery design and validation; delivery tools; generation and analysis of engineering materials; and crop genome engineering applications. The chapters cover topics such as methods of applying the popular CRISPR-Cas9 or CRISPR-Cas12 systems for editing genomes in different crop species, the use of small synthetic plastome for potato genome engineering, and the use of CRISPR-Cas9 for algal cell genome engineering. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

(more…)

The Pearl Millet Genome


Free Download The Pearl Millet Genome by Rakesh K. Srivastava, C. Tara Satyavathi, Rajeev K. Varshney
English | PDF EPUB (True) | 2024 | 154 Pages | ISBN : 303156975X | 15.2 MB
This book entitled, The Pearl Millet Genome, is the first comprehensive compilation of deliberations on history, domestication, genetic and genomic resources, traditional breeding, genetic diversity, molecular maps and mapping of important biotic stress as well as nutritional quality traits, whole genome sequencing and comparative genomics, functional genomics, genetic transformation. The economic, nutritional, and health importance of the pearl millet is also discussed. It also presents the input use efficiency and wide adaptation of the crop. Altogether, the book will contain about 200 pages over 10 chapters authored by globally reputed experts on the relevant field in this crop. This book will be useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, pathology, molecular genetics and breeding, genetic engineering, structural and functional genomics, and nutritional quality aspects of the crop. This book will also be also useful to seed and pharmaceutical industries.

(more…)