Tag: Genomics

Free Download Genetics, Genomics and Breeding of Seed Spices by Chittaranjan Kole
English | EPUB (True) | 2024 | 224 Pages | ISBN : 9819796296 | 13.1 MB
This volume presents detailed reviews on biochemistry, classical genetics and traditional breeding, germplasm diversity, molecular genetics, tissue culture, biotechnology, and structural and functional genomics of ten major seed spices including ajwain, anise, celery, coriander, cumin, dill, fennel, fenugreek, Nigella and parsely.

Free Download Genetics, Genomics and Breeding of Seed Spices
English | 2024 | ISBN: 9819796296 | 224 Pages | PDF (True) | 12 MB
This volume presents detailed reviews on biochemistry, classical genetics and traditional breeding, germplasm diversity, molecular genetics, tissue culture, biotechnology, and structural and functional genomics of ten major seed spices including ajwain, anise, celery, coriander, cumin, dill, fennel, fenugreek, Nigella and parsely.

Free Download Clinical Genetics and Genomics at a Glance
by Neeta Lakhani, Kunal Kulkarni, Julian Barwell, Pradeep Vasudevan, and Huw Dorkins
English | 2024 | ISBN: 1119240956 | 269 pages | True PDF | 75.78 MB

Free Download Fungal Genomics
English | 2024 | ISBN: 3031756657 | 218 Pages | PDF EPUB (True) | 29 MB
Part I Genome Sequences and Beyond: Examines the impact of genome-based information and techniques on research ranging from the discovery of giant transposons to the analysis of less-studied extremotolerant fungi as well as studies of three-dimensional chromatin organization in fungi.

Free Download Comparative Genomics: RECOMB 2005 International Workshop, RCG 2005, Dublin, Ireland, September 18-20, 2005. Proceedings By Abraham Bachrach, Kevin Chen, Chris Harrelson, Radu Mihaescu (auth.), Aoife McLysaght, Daniel H. Huson (eds.)
2005 | 168 Pages | ISBN: 3540289321 | PDF | 4 MB
This book constitutes the refereed proceedings of the RECOMB 2005 Satellite Workshop, the 3rd RECOMB Comparative Genomics meeting RCG 2005, held in Dublin, Ireland in September 2005.The 14 revised full papers presented were carefully reviewed and selected from 21 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.

Free Download Eduard Torrents, "Ribonucleotide Reductase Family: Genetics and Genomics: Genetics & Genomics"
English | ISBN: 1606924192 | 2009 | 99 pages | PDF | 6 MB
Ribonucleotide reductase (RNR), a universal enzyme present in essentially all living cells and organisms, has a central role in DNA replication and repair by catalysing production of deoxyribonucleotides from the corresponding ribonucleotides. Three major classes of RNRs are known, differing in their cofactor requirements: class I RNRs (with subclasses Ia and Ib) carry a stable tyrosyl radical and are oxygen-dependent, class II RNRs require the vitamin B12 cofactor 5′-deoxyadenosylcobalamin and are oxygen-independent, and class III RNRs carry a stable glycyl radical and are oxygen-sensitive. Despite these differences, all classes have a similar reaction mechanism and the same highly specific catalytic core structure, indicating that they evolved from a common ancestor. Biochemical studies of RNRs from selected model organisms in combination with the vast number of deduced RNR sequences from publicly available complete genomic sequences show that whereas eukaryotes and their viruses with few exceptions contain only class Ia RNRs, all three major RNR classes are found among prokaryotes and bacteriophages and quite often one organism encodes more than one class of RNR. They are compiled in an open access database, called RNRdb for Ribonucleotide Reductase database that is available athttp://rnrdb.molbio.su.se. RNRs are produced in a strictly controlled way depending upon growth phase and environmental cues. The authors describe a comprehensive summary of how the expression of RNR genes is regulated in several eubacterial organisms and in yeast. Due to RNR’s importance for the realisation of DNA replication, it has been recognised as a possible target for antiproliferative therapy. The authors present a comprehensive summary of RNR-specific inhibitors that have reached clinical trials and/or are currently used in clinical therapy.

Free Download Ramaswamy Govindan MD, "Cancer Genomics for the Clinician"
English | ISBN: 0826168671 | 2019 | 184 pages | PDF | 10 MB
Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more.

Free Download Dictyostelids: Evolution, Genomics and Cell Biology By Sandra Muñoz-Braceras, Ana Mesquita, Ricardo Escalante (auth.), Maria Romeralo, Sandra Baldauf, Ricardo Escalante (eds.)
2013 | 255 Pages | ISBN: 3642384862 | PDF | 6 MB
Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.

Free Download Terry J. McGenity, "Taxonomy, Genomics and Ecophysiology of Hydrocarbon-Degrading Microbes"
English | 2019 | pages: 392 | ISBN: 3030147959 | PDF | 7,3 mb
This book provides comprehensive, authoritative descriptions of the microbes involved in cleaning up oil spills and degrading climate-altering hydrocarbons such as methane, and has detailed discussions about the taxonomy, ecology, genomics, physiology and global significance of these hydrocarbon-degrading microbes.

Free Download Bovine Genomics By
2012 | 281 Pages | ISBN: 0813821223 | PDF | 3 MB
The genetic information being unlocked by advances in genomic and high throughput technologies is rapidly revolutionizing our understanding of developmental processes in bovine species. This information is allowing researchers unprecedented insight into the genetic basis of key traits. Bovine Genomics is the first book to bring together and synthesize the information learned through the bovine genome sequencing project and look at its practical application to cattle and dairy production. Bovine Genomics opens with foundational chapters on the domestication of cattle and traditional Mendelian genetics. Building on these chapters, coverage rapidly moves to quantitative genetics and the advances of whole genome technologies. Significant coverage is given to such topics as epigenetics, mapping quantitative trail loci, genome-wide association studies and genomic selection in cattle breeding. The book is a valuable synthesis of the field written by a global team of leading researchers.Providing wide-ranging coverage of the topic, Bovine Genomic, is an essential guide to the field. The basic and applied science will be of use to researchers, breeders, and advanced students.Content: Chapter 1 The Origins of Cattle (pages 1-10): Matthew D. Teasdale and Daniel G. BradleyChapter 2 Mendelian Inheritance in Cattle (pages 11-19): Frank W. NicholasChapter 3 Genetics of Coat Color in Cattle (pages 20-33): Sheila M. SchmutzChapter 4 From Quantitative Genetics to Quantitative Genomics: A Personal Odyssey (pages 34-50): Morris SollerChapter 5 Cartography of the Bovine Genome (pages 51-62): James E. WomackChapter 6 History of Linkage Mapping the Bovine Genome (pages 63-74): Stephanie D. McKay and Robert D. SchnabelChapter 7 Bovine X and Y Chromosomes (pages 75-100): F. Abel Ponce de Leon and Wansheng LiuChapter 8 Cattle Comparative Genomics and Chromosomal Evolution (pages 101-108): Denis M. LarkinChapter 9 Sequencing the Bovine Genome (pages 109-122): Kim C. Worley and Richard A. GibbsChapter 10 Bovine Genome Architecture (pages 123-143): David L. AdelsonChapter 11 Bovine Epigenetics and Epigenomics (pages 144-168): Xiuchun (cindy) TianChapter 12 Mapping Quantitative Trait Loci (pages 169-191): Joel I. WellerChapter 13 Genome?Wide Association Studies and Linkage Disequilibrium in Cattle (pages 192-210): M. E. Goddard and B. J. HayesChapter 14 Genomic Selection in Beef Cattle (pages 211-233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. SchnabelChapter 15 Impact of High?Throughput Genotyping and Sequencing on the Identification of Genes and Variants Underlying Phenotypic Variation in Domestic Cattle (pages 234-258): Michel Georges