Tag: Immune

Mechanisms of Lymphocyte Activation and Immune Regulation VI Cell Cycle and Programmed Cell Death in the Immune System


Free Download Mechanisms of Lymphocyte Activation and Immune Regulation VI: Cell Cycle and Programmed Cell Death in the Immune System By Sudhir Gupta (auth.), Sudhir Gupta, J. John Cohen (eds.)
1996 | 270 Pages | ISBN: 1489902767 | PDF | 10 MB
Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described splice variants and their influence on apoptosis are also reviewed, and the role of the members of the Bcl-2 family in apoptosis is discussed in detail. Part III reviews various aspects of apoptosis in B lymphocytes, including mechanisms that regulate apoptosis/survival of B lymphocytes and the regulation of Fas-mediated apoptosis in B lymphocytes.

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Brain Immune System Signal Molecules in Protection from Aerobic and Anaerobic Infections


Free Download Brain Immune System Signal Molecules in Protection from Aerobic and Anaerobic Infections By Armen A. Galoyan (auth.)
2012 | 200 Pages | ISBN: 1461436664 | PDF | 4 MB
Proline-rich polypeptides – in particular (PRP-1) galarmin and its structural analogues – are, when isolated from the neurosecretory granules of neurohypophysis of humans and animals, a new type of hypothalamic peptides. They work against aerobic, anaerobic, gram-positive, and gram-negative microorganisms in vivo, and do not have etiotropic properties. They are unique and capable substitutes to antibiotics, and, moreover, may be effective against strains, such as MRSA, that develop resistance to antibiotics. Galarmin, a component of the brain neuroendocrine system produced by the neurosecretory cells of hypothalamus, possesses immunomodulative, neuroprotective, antioxidant, antitumorigenic and hematopoietic properties. Moreover, galarmin and its structural analogues are powerful anti-inflammatory compounds. In addition to presenting a full overview of the neuroimmune system, it emphasizes the antibacterial, neuroprotective, and neuroregenerative properties of proline-rich polypeptides. It investigates the mechanism of galarmin’s action during different infectious processes, where it targets such dangerous pathogens as Bacillus anthracis, Clostridium perfringens, Mycobacterium tuberculosis, and Methycillin resistant Staphylococcus aureus. This research is important from both a theoretical and a clinical point of view, creating new prospects for the modern pharmaceutical industry and neuroendocrine, neuroimmunological sciences.Dr. Galoyan is a pioneer of the specialized field of neuroimmunology. During his 45-year long career, he has discovered a neuroendocrine immune system of the brain and identified a new type of brain cytokines: proline-rich polypeptides. The most important of these, PRP-1 (galarmin) has been shown to possess antibacterial properties and protect from certain neurotoxins.

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Immune-Mediated Myopathies and Neuropathies Current Trends and Future Prospects


Free Download Immune-Mediated Myopathies and Neuropathies: Current Trends and Future Prospects by Balan Louis Gaspar
English | February 22, 2023 | ISBN: 9811984204 | 306 pages | MOBI | 9.97 Mb
The book covers all aspects of immune-mediated diseases of the muscle and nerve, which are a group of complex diseases, whose diagnosis needs a team of specialists in the field of neuropathology, immunopathology, neurology, and rheumatology. Nerve and muscle biopsy evaluation is invaluable in distinguishing immune-mediated from etiologies and therefore, despite being invasive, pathological evaluation of nerve and muscle has stood the test of time. Chapters cover all the essential aspects of each disease entity viz. the pathogenesis, clinical features, diagnostic armamentarium, and guidelines for diagnosis and management. It is supplemented with full-colorful illustrations and photomicrographs for better comprehension. It includes a chapter highlighting the current progress in the field of immune-mediated myopathies and neuropathies as it is a rapidly evolving field with the addition of many new entities.

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Understanding the Role of the Immune System in Improving Tissue Regeneration


Free Download Understanding the Role of the Immune System in Improving Tissue Regeneration by Health Sciences Policy
English | January 21, 2023 | ISBN: 0309688175 | 188 pages | EPUB | 3.40 Mb
The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve outcomes of tissue repair and regeneration in patients. The workshop, titled "Understanding the Role of the Immune System in Improving Tissue Regeneration," explored the role of the immune system in the success or failure of regenerative medicine therapies. Participants considered potential strategies to effectively "prepare" patients’ immune systems to accept regenerative therapies and increase the likelihood of successful clinical outcomes and also discussed risks associated with modulating the immune system. This Proceedings of a Workshop highlights the presentations and discussions that occurred during the workshop.

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Yoga and Somatics for Immune and Respiratory Health


Free Download Yoga and Somatics for Immune and Respiratory Health by Charlotte Watts
English | October 21, 2022 | ISBN: 1839970871 | 400 pages | MOBI | 16 Mb
Our respiratory and immune systems are intrinsically linked to how we relate to the world around us. Engaging with our vitality through the movement we were designed to express equips us with an invaluable ability to support the optimal functioning of our internal systems.

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Understanding the Role of the Immune System in Improving Tissue Regeneration Proceedings of a Workshop


Free Download Understanding the Role of the Immune System in Improving Tissue Regeneration: Proceedings of a Workshop
English | 2023 | ISBN: 0309688175 | 188 Pages | PDF | 3.6 MB
The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve outcomes of tissue repair and regeneration in patients.

(more…)