Tag: Mechanisms

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Free Download Dynamic Gene Control: The Epigenetic Mechanisms by Harmony Royce
English | September 11, 2024 | ISBN: N/A | ASIN: B0DGWQQ3HQ | 133 pages | EPUB | 0.53 Mb
Dynamic Gene Control: The Epigenetic Mechanisms[/center]
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Free Download Nichole D. Raskin, "Pollination: Mechanisms, Ecology and Agricultural Advances "
English | ISBN: 1612096344 | 2011 | 174 pages | PDF | 7 MB
This continuing series presents original research results on the leading edge of psychology. This book reviews research on the role of child sexual abuse in the development of psychopathology; enduring personality change after catastrophic experience; the neurobiology of anxiety and affective disorders; the genetics of panic disorders; perceptual motor skills and the cognitive architecture of action; gender issues and implications in depression and suicide; alexithymia and mental health and personality characteristics in men suffering from chronic tension-type and cervicogenic headaches.

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Free Download Leonzio Galella, "Vasopressin: Mechanisms of Action, Physiology and Side Effects "
English | ISBN: 162417311X | 2013 | 115 pages | PDF | 4 MB
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Free Download Organisation for Economic Co-operation and Development, "Using Market Mechanisms to Manage Fisheries: Smoothing the Path"
English | 2006 | pages: 323 | ISBN: 9264036571 | PDF | 2,6 mb
This report explores the various ways OECD countries have used markets to enhance fisheries management and how they have addressed trade-offs between different fishing interests. The first three chapters analyze the characteristics of territorial use rights in fisheries, community-based catch quotas, vessel catch limits, individual non-transferable quotas, and individual transferable quotas. The remainder of the book surveys the use of market mechanisms in Iceland, Japan, Korea, Norway, Spain, United Kingdom, and United States. No index is provided. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

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Free Download Flora Fitzgerald, "Photodynamic Therapy: Principles, Mechanisms and Applications"
English | ISBN: 1536119121 | 2017 | 223 pages | PDF | 6 MB
In Chapter One, the basic mechanisms, applications and functional nanomaterials-based drug delivery systems for photodynamic therapy of cancer are reviewed. Chapter Two summarizes the application of different carbon based nanomaterials as agents for PDT and discusses current state-of-the-art use of fullerenes and their derivatives, carbon nanotubes and graphene quantum dots in PDT. Chapter Three covers the benefits and pitfalls of using chemi- and bioluminescent systems as intracellular excitation sources in PDT. Bioluminescence is a widespread natural phenomenon, which consists on emission of light resulting from the oxidation of a substrate in a reaction catalyzed by an enzyme in a biological system. Chapter Four addresses in the synthesis, characterization, and photodynamic activity of a novel hydrophobic photosensitizer 5,10,15,20-tetrakis(benzothiophene) Porphyrin (BTP) and water soluble photosensitizer 5,10,15,20-Tetrakis(7- sulfonatobenzothiophene) Porphyrin (SBTP). Chapter Five discusses the "Guidelines for Gastroenterological Endoscopy in Patients on Oral Antithrombotic Treatment" established by the Japan Gastroenterological Endoscopy Society (JGES).These guidelines classify endoscopic interventions according to the risk of hemorrhage and specify the management of various antithrombotic drugs. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are classified as high-risk procedures for hemorrhage, but PDT is not included in the guidelines. Because PDT causes ischemic necrosis of tumor tissue, the authors say this could possibly be performed safely in patients on oral antithrombotic therapy. The authors of Chapter Six developed a method of the initial concentration of protoporphyrin-IX in the operated removing glioblastoma tissue using the calibration curve of the fluorescent intensity and the known Pp-IX concentration in order to estimate of the more correlated with the cure rate.[/center]
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Free Download Mechanisms of Lymphocyte Activation and Immune Regulation VI: Cell Cycle and Programmed Cell Death in the Immune System By Sudhir Gupta (auth.), Sudhir Gupta, J. John Cohen (eds.)
1996 | 270 Pages | ISBN: 1489902767 | PDF | 10 MB
Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described splice variants and their influence on apoptosis are also reviewed, and the role of the members of the Bcl-2 family in apoptosis is discussed in detail. Part III reviews various aspects of apoptosis in B lymphocytes, including mechanisms that regulate apoptosis/survival of B lymphocytes and the regulation of Fas-mediated apoptosis in B lymphocytes.

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Free Download Fatigue: Neural and Muscular Mechanisms By Brenda R. Bigland-Ritchie (auth.), Simon C. Gandevia, Roger M. Enoka, Alan J. McComas, Douglas G. Stuart, Christine K. Thomas, Patricia A. Pierce (eds.)
1995 | 542 Pages | ISBN: 1489910182 | PDF | 17 MB
This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.

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Free Download Mechanisms of Mineralization of Vertebrate Skeletal and Dental Tissues by Irving M. Shapiro , William J. Landis
English | EPUB (True) | 513 Pages | ISBN : 3031343026 | 119.5 MB
The book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues.

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Free Download Epigenetic Mechanisms in Breast Cancer Therapy and Resistance
English | 2024 | ISBN: 3031666852 | 111 Pages | PDF EPUB (True) | 21 MB
Epigenetic mechanisms are essential for normal mammalian development and maintenance of gene expression patterns. Disruption of epigenetic processes can lead to altered transcriptional regulation, gene levels, and malignant cellular transformation. Global alterations of the epigenetic landscape are a hallmark of tumorigenesis and metastasis. Conventionally, cancer was thought to be a genetic disease, but recent advancement in the field identified an abundance of epigenetic abnormalities along with genetic alterations. The extensive reprogramming of epigenetic machinery in cancer includes DNA methylation, histone modifications, nucleosome positioning and non-coding RNAs, specifically microRNA expression. Additionally, the reversible nature of epigenetic aberrations has led to the emergence of the promising field of epigenetic therapy, and recent FDA approval of epigenetic drugs for cancer treatment.

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Free Download ESKAPE Pathogens: Detection, Mechanisms and Treatment Strategies by Siddhardha Busi, Ram Prasad
English | March 30, 2024 | ISBN: 9819987989 | 556 pages | MOBI | 7.56 Mb
This book explores the medical importance of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (ESKAPE) pathogens, and the challenges posed by antibiotic resistance. It covers the antibiotic resistance profile and detection of ESKAPE pathogens, as well as the mechanistic understanding of antibiotic resistance in these pathogens. The book discusses standard microbiological techniques, including staining, morphological and cultural characteristics, biochemical properties, and serotyping, as well as nucleic acid amplification and molecular diagnostic techniques for the detection of ESKAPE pathogens. In addition, the book explores biochemical, molecular, and computational techniques for the determination of virulence factors of ESKAPE pathogens. It also examines the synthesis, structure, function, and inhibitors of virulence factors and biofilm componentsin these pathogens. The book explores various strategies for combating ESKAPE pathogens, including antibiotic adjuvants and their synergistic activity, phytochemicals as potential antibacterial agents, photodynamic therapy, antimicrobial peptides and antibacterial antibodies, antimicrobial activity of Nanomaterials and Nanocomposites, and bacteriophage therapy. Finally, the book discusses in silico and computational approaches for the inhibition of ESKAPE pathogens. This comprehensive book is of interest to researchers, students, and healthcare professionals interested in the diagnosis, prevention, and treatment of ESKAPE pathogens.

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