Tag: Neuropsychiatric

Free Download Transgenic and Knockout Models of Neuropsychiatric Disorders By Gene S. Fisch (auth.), Gene S. Fisch PhD, Jonathan Flint MD, MRCPsych (eds.)
2006 | 296 Pages | ISBN: 1588295079 | PDF | 2 MB
Neuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, as well as speech disorders, and disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder. Timely introductory articles debate the alleged continuity of species of human and infrahuman behavior (Darwin), the utility of infrahuman animals in understanding human behavior and psychiatric disease, and the suitability of nonhuman models of complex neuropsychiatric dysfunctions involving language. Comprehensive and systematic, Transgenic and Knockout Models of Neuropsychiatric Disorders offers a clear assessment of whether genetic abnormalities produced from infrahuman models manifest the neuropsychiatric disorders to which they correspond in humans and how best they may be used to carry out successful research today.

Free Download Molecular and Cell Biology of Neuropsychiatric Diseases By F. Owen, Ruth Itzhaki
2012 | 201 Pages | ISBN: 9401043051 | PDF | 13 MB
The fourth volume in the Molecular and Cell Biology of Neuropsychiatric Diseases series provides a comprehensive, timely review of the use of modern biological techniques in the investigation of the major neuropsychiatric diseases. The scope of the book is wide, and an introductory section at the beginning of each chapter enables non-specialist and specialist alike to appreciate the significance of this research.

Free Download Neuropsychiatric Manifestations in Neurological Diseases
English | 2024 | ISBN: 9819718201 | 206 Pages | PDF EPUB (True) | 4 MB
Psychiatric symptoms (or mood/emotional disturbances) are diverse in patients with neurological diseases, that include depression, anxiety, emotional incontinence, anger, fatigue, and apathy. These symptoms are common; more than 1/3 of the patients suffer from these symptoms. Unfortunately, they have been neglected because 1) unlike other neurological symptoms such as motor dysfunction, speech disturbances or visual field defect, these symptoms are not visible and difficult to be noticed unless they are specifically examined by a physician who is properly educated on this problem 2) they are often not regarded as neurological symptoms either by the patients or their caregivers 3) they are relatively poorly studied by both neurologists and psychiatrists, and accordingly, are unfamiliar to the physicians. Especially, although `depression’ is well known to physicians, other symptoms such as emotional incontinence, anger, fatigue or apathy are not appropriately assessed by physicians, and frequently misdiagnosed as depression. Moreover, there are difficulties in diagnosing depression in patients neurological diseases. For example, the individual items included in depression diagnosis such as sleep disturbances, appetite loss, or fatigue can result from neurological diseases or comorbid physical conditions in patients with neurological diseases. Therefore, a diagnosis of `depression’ should be made cautiously. Finally, it should be understood that the importance of different mood/ emotional syndromes differ among various neurological diseases; for instance, although emotional incontinence and anger occur in as many as 20-30 % of stroke patients, apathy and fatigue are more important symptoms than these for patients with neuro-degenerative disease.