Tag: Pathogenesis

Crohn’s Disease Etiology, Pathogenesis and Interventions


Free Download Jack N. Cadwallader, "Crohn’s Disease: Etiology, Pathogenesis and Interventions"
English | ISBN: 160456993X | 2008 | 246 pages | PDF | 4 MB
This book is devoted to research on Crohn’s disease (also known as regional enteritis)which is a chronic, episodic, inflammatory bowel disease (IBD) and is generally classified as an auto-immune disease. Crohn’s disease can affect any part of the gastrointestinal tract from mouth to anus; as a result, the symptoms of Crohn’s disease vary among afflicted individuals. The disease is characterised by areas of inflammation with areas of normal lining between in a symptom known as skip lesions. The main gastrointestinal symptoms are abdominal pain, diarrhoea (which may be bloody, though this may not be visible to the naked eye), constipation, vomiting, weight loss or weight gain. Crohn’s disease can also cause complications outside of the gastrointestinal tract such as skin rashes, arthritis, and inflammation of the eye. Although the cause of Crohn’s disease is not known, it is believed to be an auto-immune disease that is genetically linked. The highest relative risk occurs in siblings, affecting males and females equally. Smokers are three times more likely to get Crohn’s disease. Unlike the other major types of IBD, there is no known drug based or surgical cure for Crohn’s disease. Treatment options are restricted to controlling symptoms, putting and keeping the disease in remission and preventing relapse.

(more…)

Pathogenesis How germs made history


Free Download Pathogenesis: How germs made history by Jonathan Kennedy
English | January 1, 2023 | ISBN: 1911709054 | 384 pages | PDF | 9.36 Mb
A BBC RADIO 4 BOOK OF THE WEEK’Powerfully argued… Fascinating and pacy’ Sunday Times, Book of the Week’Superbly written… sure to please readers of Yuval Noah Harari or Rutger Bregman’ The Times’Full of amazing facts’ Observer’The book shines when it brings cutting-edge science to bear’ Financial Times’A dizzying range of material’ The Economist’A humbling story for humankind’ SpectatorChallenges some of the greatest cliches about colonialism… A revelation’ SATHNAM SANGHERA’Thrilling and eye-opening’ LEWIS DARTNELL’Science and history at its best’ MARK HONIGSBAUM’Unpicks everything we thought we knew… Mind blowing’ CAL FLYNIn this revelatory book, Dr Jonathan Kennedy argues that germs have shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam.How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? And why did the Industrial Revolution lead to the birth of the modern welfare state?The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are. Indeed, the only reason humans don’t lay eggs is that a virus long ago inserted itself into our DNA, and there are as many bacteria in your body as there are human cells. We have been thinking about the survival of the fittest all evolution is not simply about human strength and intelligence, but about how we live and thrive in a world dominated by microbes.By exploring the startling intimacy of our relationship with infectious diseases, Kennedy shows how they have been responsible for some of the seismic revolutions of the past 50,000 years. Provocative and brimming with insight, Pathogenesis transforms our understanding of the human story, revealing how the crisis of a pandemic can offer vital opportunities for change.

(more…)

Irritable Bowel Syndrome Diagnosis, Pathogenesis and Treatment Options


Free Download Magdy El-salhy, "Irritable Bowel Syndrome: Diagnosis, Pathogenesis and Treatment Options "
English | ISBN: 1620815524 | 2012 | 149 pages | PDF | 4 MB
Irritable bowel syndrome (IBS) is common and affects 5 to 20% of individuals world-wide. Physicians with various specialties and at different settings are bound to meet these patients. This book is written by clinicians with long experience with IBS patients at different settings that have performed active research on IBS from different angles. Topics discussed include the prevalence and incidence of IBS world-wide, symptoms and consequences for patients and the society; IBS symptom based diagnosis; pathogenesis and the different possible etiological factors; a new hypothesis for the pathogenesis of IBS; post-infectious and inflammatory bowel disease (IBD) associated IBS and treatment options, both non-pharmacological and pharmacological. This book does not only contain up to date data, but also included are the authors’ points of view and their argument in several debated issues in IBS.

(more…)

Prostate Cancer Advancements in the Pathogenesis, Diagnosis and Personalized Therapy


Free Download Prostate Cancer: Advancements in the Pathogenesis, Diagnosis and Personalized Therapy by Gordana Kocic, Jovan Hadzi-Djokic, Tatjana Simic
English | March 21, 2024 | ISBN: 3031517113 | 408 pages | MOBI | 6.05 Mb
This book provides an in-depth exploration of the biology of prostate cancer, from its cellular origins to its clinical manifestations and therapeutic options. In addition to thoroughly covering a variety of diagnostic methods, radical procedures, radiation therapy, hormone therapy, and surgical techniques for prostatectomy, the book seeks to improve the understanding of the development of prostate cancer.

(more…)

Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases Volume II Kidney, Central Nervous System,


Free Download Mitesh Kumar Dwivedi, "Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases: Volume II: Kidney, Central Nervous System,"
English | ISBN: 9811947996 | 2022 | 563 pages | PDF | 9 MB
This book, which is the second volume of Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases, provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting in autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases.Contributions in the book focus on the role of microbiota/probiotics and their distinct mechanisms exerted in the management of autoimmune diseases of the kidney, central nervous system, eye, blood vessel, and bowel. This could help in better understanding to design of therapeutic strategies that can be deployed to prevent these autoimmune diseases.The book has an interdisciplinary appeal and scholars with an interest in immunology, medical microbiology, and nutritional sciences will value its contribution. Overall, the book gives new dimension and insight into the aspects of microbial role in autoimmune disease pathogenesis.

(more…)

Pathology of Lung Disease Morphology – Pathogenesis – Etiology


Free Download H.: Popper, "Pathology of Lung Disease: Morphology – Pathogenesis – Etiology"
English | 2017 | pages: 719 | ISBN: 3662504898, 3662570645 | EPUB | 93,2 mb
This well-illustrated textbook covers the full range of lung and pleural diseases from the pathologic standpoint. Both diseases of adults and pediatric lung diseases are presented. The book will serve as an excellent guide to the diagnosis of these diseases, but in addition it explains the disease mechanisms and etiology. Genetics and molecular biology are also discussed whenever necessary for a full understanding. The author is an internationally recognized expert who runs courses on lung and pleural pathology attended by participants from all over the world. In compiling this book, he has drawn on more than 30 years’ experience in the field.

(more…)