Tag: Proteins

Free Download Biomacromolecules
by Mohamed Elzagheid
English | 2025 | ISBN: 3111582981 | 178 pages | True PDF EPUB | 22.91 MB

Free Download Plant-Based Proteins: Production, Physicochemical, Functional, and Sensory Properties
English | 2025 | ISBN: 1071642715 | 442 Pages | PDF (True) | 37 MB
This volumes provides a comprehensive guide to the research and development of plant-based proteins. Chapters coversprotocols and guidelines needed for plant-based protein research and development, from sourcing and processing to the analysis of the physical, chemical, functional, and sensory properties of these proteins. Written in the format of the Methods and Protocols in Food Science series, the chapters include an introduction to the respective topic, list necessary materials and reagents, detail well established and validated methods for readily reproducible laboratory protocols and contain notes on how to avoid or solve typical problems.

Free Download Moonlighting Cell Stress Proteins in Microbial Infections By Peter A. Lund (auth.), Brian Henderson (eds.)
2013 | 406 Pages | ISBN: 9400767862 | PDF | 8 MB
Microbial infection is increasingly seen as a problem as we begin to run out of antibiotics. Understanding how microbes cause disease is essential. In recent years it has begun to emerge that bacteria, fungi, protozoa and viruses can use their cell stress proteins to cause infection. This volume brings together the world’s leading experts in the study of the microbial and human cell stress proteins that are involved in enabling microorganisms to infect humans and cause serious disease.

Free Download Dispersity, Structure and Phase Changes of Proteins and Bio Agglomerates in Biotechnological Processes by Arno Kwade, Ingo Kampen
English | PDF EPUB (True) | 2024 | 548 Pages | ISBN : 3031631633 | 167.4 MB
This book serves as a comprehensive summary of the priority program SPP 1934, which focused on understanding the dispersity, structure, and phase changes of proteins and bio-agglomerates in biotechnological processes. Through contributions from various research groups, the program explored how sensitive proteins and bio-agglomerates are affected by the process environment during fermentation, downstream processing, and formulation. It investigated these effects across three size scales: microscale, encompassing single proteins, clusters, crystals, and virus-like particles; mesoscale, focusing on cells and cell clusters; and macroscale, examining overall process dynamics. The main objective was to enhance biotechnological process chains by elucidating the mechanical, thermal, and chemical stresses that impact protein and bio-agglomerate structures. By gaining insights into these stressors, the program aimed to enable precise control measures to mitigate denaturation and unfavorable growth of proteins and cells. This compilation seeks to contribute to the optimization of biotechnological processes, facilitating advancements in various industries.

Free Download Biophysical Analysis of Membrane Proteins: Investigating Structure and Function By
2007 | 368 Pages | ISBN: 3527316779 | PDF | 5 MB
Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new insights. Following an introduction, further sections discuss structural approaches, molecular interaction and large assemblies, dynamics and spectroscopies, finishing off with an exploration of structure-function relationships in whole cells.Content: Chapter 1 High?Resolution Structures of Membrane Proteins: From X?Ray Crystallography to an Integrated Approach of Membranes (pages 1-27): Prof. Eva Pebay?PeyroulaChapter 2 Membrane Protein Structure Determination by Electron Cryo?Microscopy (pages 29-54): Christopher G. Tate and John L. RubinsteinChapter 3 Introduction to Solid?State NMR and its Application to Membrane Protein-Ligand Binding Studies (pages 55-87): Krisztina Varga and Anthony WattsChapter 4 Analytical Ultracentrifugation: Membrane Protein Assemblies in the Presence of Detergent (pages 89-120): Christine Ebel, Jesper V. Moller and Marc le MaireChapter 5 Probing Membrane Protein Interactions with Real?Time Biosensor Technology (pages 121-140): Iva Navratilova, David G. Myszka and Rebecca L. RichChapter 6 Atomic Force Microscopy: High?Resolution Imaging of Structure and Assembly of Membrane Proteins (pages 141-158): Simon Scheuring, Nikolay Buzhynskyy, Rui Pedro Goncalves and Szymon JaroslawskiChapter 7 Molecular Dynamics Studies of Membrane Proteins: Outer Membrane Proteins and Transporters (pages 159-185): Syma Khalid, John Holyoake and Mark S. P. SansomChapter 8 Understanding Structure and Function of Membrane Proteins Using Free Energy Calculations (pages 187-211): Christophe Chipot and Klaus SchultenChapter 9 Neutrons to Study the Structure and Dynamics of Membrane Proteins (pages 213-240): Kathleen Wood and Giuseppe ZaccaiChapter 10 Circular Dichroism: Folding and Conformational Changes of Membrane Proteins (pages 241-258): Nadege Jamin and Jean?Jacques LacapereChapter 11 Membrane Protein Structure and Conformational Change Probed using Fourier Transform Infrared Spectroscopy (pages 259-288): John E. Baenziger and Corrie J. B. daCostaChapter 12 Resonance Raman Spectroscopy of a Light?Harvesting Protein (pages 289-307): Andrew Aaron Pascal and Bruno RobertChapter 13 Energy Transfer Technologies to Monitor the Dynamics and Signaling Properties of G?Protein?Coupled Receptors in Living Cells (pages 309-334): Jean?Philippe Pin, Mohammed?Akli Ayoub, Damien Maurel, Julie Perroy and Eric Trinquet

Free Download Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition By
1999 | 564 Pages | ISBN: 3527283153 | PDF | 25 MB
In the field of medicinal biotechnology three major developments have caused a revolution in research that has a lot of innovative effects on clinical medicine and future applications on humans. With the availability of tailored recombinant proteins and the opportunity to produce high amounts of monoclonal antibodies new diagnostic applications have emerged and many therapeutic perspectives, e.g. in the treatment of multiple sclerosis and of cancer, are being discussed today. The aim of somatic gene therapy is to re-establish normal cell function by supplying the cells with the respective intact gene. This is a very difficult task and different diseases, e.g. AIDS and several metabolic disorders, are under investigation now. So far first promising approaches exist in cancer therapy. Moreover the book informs about regulatory and economic aspects of these new methods and their applications. Content: Chapter 1 Types and Function of Proteins (pages 1-41): Sabine Wolf and Hans Gunter GassenChapter 2 Sequence and Structure of Proteins (pages 43-86): Frank Eisenhaber and Peer BorkChapter 3 Protein Interactions (pages 87-108): Michael Meyer and Dietmar SchomburgChapter 4 In vitro Folding of Inclusion Body Proteins on an Industrial Scale (pages 110-123): Rainer Rudolph, Hauke Lilie and Elisabeth SchwarzChapter 5 Medical Applications of Recombinant Proteins in Humans and Animals (pages 125-188): Gayle Delmonte WetzelChapter 6 Enzymes for Industrial Applications (pages 189-216): Wolfgang Aehle and Onno MissetChapter 7 Antibody Engineering and Expression (pages 218-244): John R. AdairChapter 8 Manufacture of Therapeutic Antibodies (pages 245-274): Andrew J. Racher, Jerry M. Tong and Julian BonnerjeaChapter 9 Use of Antibodies for Immunopurification (pages 275-288): David J. KingChapter 10 Preclinical Testing of Antibodies: Pharmacology, Kinetics and Immunogenicity (pages 289-302): Roly Foulkes and Sue StephensChapter 11 Preclinical Testing of Antibodies: Safety Aspects (pages 303-310): Ronald W. JamesChapter 12 Therapeutic Applications of Monoclonal Antibodies: A Clinical Overview (pages 311-326): Mark SopwithChapter 13 Antibodies for Sepsis: Some Lessons Learnt (pages 328-341): Steven M. OpalChapter 14 An Engineered Human Antibody for Chronic Therapy: CDP571 (pages 343-353): Mark Sopwith and Sue StephensChapter 15 Antibody Targeted Chemotherapy (pages 355-364): Mark S. Berger, Philip R. Hamann and Mark SopwithChapter 16 ReoPro Clinical Development: A Case Study (pages 365-380): Harlan F. WeismanChapter 17 Overview of Gene Therapy (pages 382-393): Andrew MountainChapter 18 Viral Vectors for Gene Therapy (pages 395-425): Barrie J. CarterChapter 19 Non?Viral Vectors for Gene Therapy (pages 427-441): Neil WeirChapter 20 Issues of Large?Scale Plasmid DNA Manufacturing (pages 443-469): Martin SchleefChapter 21 Gene Therapy for HIV Infection (pages 471-492): Mark C. Poznansky, Myra McClure and Gregor B. AdamsChapter 22 Regulation of Antibodies and Recombinant Proteins (pages 494-516): Julie Foulkes and Gillian TraynorChapter 23 Regulation of Human Gene Therapy (pages 517-530): James ParkerChapter 24 Economic Considerations (pages 531-542): Ian J. Nicholson

Free Download CCN Proteins: Methods and Protocols (Methods in Molecular Biology) by Masaharu Takigawa
English | November 13, 2022 | ISBN: 1071627430 | 444 pages | EPUB | 56 Mb
This second edition volume expands on the previous edition with updated methodologies and practical tips to overcome obstacles associated with experimentation pertaining to chemistry, biology, physiology, pathology, medical and dental sciences, and pharmacology of CCN proteins. The chapters in this book cover topics such as CCN4 immunofluorescence for tissue microarray; utilizing public molecular biological databases for CCN family research; the effects of CCN4 on pancreatic beta cell proliferation; gene expression analysis of CCNs; novel cell biological assays for measuring bone remodeling activities of CCN proteins; and the function of CCN2 in tubular epithelium cells with a focus on renal fibrogenesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Free Download A Malcolm Campbell, Christopher J Paradise, "Using DNA Information to Make Proteins"
English | 2016 | ISBN: 1944749179 | EPUB | pages: 100 | 3.8 mb
Many people were taught that DNA is the "blueprint of the cell," but what does that really mean? If taken literally, it would reveal a static image of what the cell looks like, but that would be incorrect. DNA codes the necessary information to produce a living being but the DNA itself is insufficient to bring a cell to life. DNA must be transcribed into segments of RNA and the RNA must generate proteins from unassembled amino acids. The conversion of DNA information into functional proteins is often referred to as central dogma, which reflects its critical role in life. However, every cell in a body contains the same genes but only a subset of genes is needed to be activated in any given cell for a cell to function properly. This book will explore many of the classic experiments that led to our current understanding central dogma. Furthermore, real data are used to discover that central dogma information is not linear and that cells must cut and paste together segments of RNA in order to build the functional proteins of cells.

Free Download The Medical Biology Guide to Proteins
by David Aebisher;
English | 2023 | ISBN: 9798886979107 | 158 pages | True PDF | 10.93 MB

Free Download Biomolecules: From Genes to Proteins (De Gruyter Textbook) by Shikha Kaushik, Anju Singh
English | April 3, 2023 | ISBN: 311079375X | 160 pages | MOBI | 6.02 Mb
Biochemistry is the study of the structure and functions of biological macromolecules such as nucleic acids, proteins, carbohydrates and lipids. The book is organized in five chapters which covers the basic concepts and fascinating chemistry of biomolecules. It also exposes students to different metabolic pathways and concept of energy in biological system, and provides valuable material for the students of Chemistry, Biochemistry, Biotechnology and Bioscience.