Tag: Synaptic

Multidisciplinary Tools for Investigating Synaptic Plasticity


Free Download Multidisciplinary Tools for Investigating Synaptic Plasticity By Jane Beil, Isabelle M. Mansuy, Thorsten Buch (auth.), Peter Nguyen (eds.)
2013 | 274 Pages | ISBN: 1627035168 | PDF | 5 MB
Investigations involving incisive mechanistic dissection of various types of synaptic plasticity have revealed that it plays key roles in neural development, sensory information processing, cortical remapping following brain injury, perception, and behavioral learning and memory. Disruptions of synaptic plasticity may underlie neurological and behavioral disorders such as Alzheimer disease, Fragile-X syndrome, autism, and drug addiction. Multidisciplinary Tools for Investigating Synaptic Plasticity, therefore, assembles expert contributions that highlight techniques and strategies used in probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Divided into three sections, this meticulous volume describes biochemical and genetic strategies for studying synaptic plasticity, behavior, neural development, and synaptogenesis, and also includes cellular electrophysiological and optical methods for interrogating a diverse array of mechanistic issues. As part of the Neuromethods series, this book contains the kind of detail and key implementation advice that maximizes successful results.Authoritative and invaluable, Multidisciplinary Tools for Investigating Synaptic Plasticity serves as an ideal primer for introducing researchers to specific techniques that will enhance their success at addressing novel questions in synaptic plasticity at the lab bench.

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New Aspects in Analyzing the Synaptic Organization of the Brain


Free Download New Aspects in Analyzing the Synaptic Organization of the Brain
English | 2024 | ISBN: 1071640186 | 436 Pages | PDF (True) | 45 MB
This volume looks at the latest methodological developments used in the field to investigate the synaptic organization of the brain from different viewpoints including structural, structural/functional, molecular, and computational methods. The chapters in this book are organized into five parts and cover topics such as preparation of brain tissue and techniques; connectivity; synaptic vesicles; phenomenological modeling; and dendritic spines. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

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Synaptic Plasticity Dynamics, Development and Disease


Free Download Synaptic Plasticity: Dynamics, Development and Disease By Ulrich Thomas, Stephan J. Sigrist (auth.), Michael R. Kreutz, Carlo Sala (eds.)
2012 | 622 Pages | ISBN: 3709109310 | PDF | 11 MB
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.

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