Tag: Targeting

Free Download Targeting the DNA Damage Response for Cancer Therapy (Cancer Treatment and Research, 186) by Timothy A. Yap, Geoffrey I. Shapiro
English | November 18, 2023 | ISBN: 3031300645 | 338 pages | MOBI | 5.67 Mb
This book discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic.

Free Download Immunotherapy in 2020: Visions and Trends for Targeting Inflammatory Disease By R. Holmdahl (auth.), A. Radbruch, H.-D. Volk, K. Asadullah, W.-D. Doecke (eds.)
2007 | 106 Pages | ISBN: 3540708502 | PDF | 2 MB
This volume features contributions from participants of the ESRF symposium on Immunotherapy in 2020-Visions and Trends for Targeting Inflammatory Diseases held in Potsdam near Berlin, Germany, in October 2006.The symposium presentations covered the main mechanisms of immunoregulation such as peripheral and central tolerance, epigenetic programming, immunologic memory, and regulatory networks in inflammation as well as novel experimental and clinical approaches for targeting inflammation in autoimmunity and transplantation.An important related question is how recent findings in immunological research can lead to improved diagnostics, new drugs, and better therapies. The targeting of novel pathways and immunoregulatory mechanisms, the challenge of immunologic memory for lastingly successful anti-inflammatory therapy, new approaches for adoptive T cell and polyclonal antibody therapies, and the individualization of immunomodulatory therapies are thereby topics of this volume.

Free Download Advanced Targeting of the Lymphatic System by Namdev Dhas, Jayvadan K. Patel, Yashwant V. Pathak
English | PDF EPUB (True) | 2024 | 517 Pages | ISBN : 3031648277 | 70.1 MB
This book goes in depth about the lymphatic system and the functions of the lymphatic organs, lymphatic tissues, and lymphatic vessels. The book addresses various types of diseases in which the lymphatic system can act as a targeting site for drug absorption and suggests strategies to treat these different infections of the lymphatic system. This book is intended for academicians who work in fields related to the lymphatic system, novel drug delivery systems, pharmaceutical science, novel-material sciences, as well as professionals in the medical, nursing, or other health care industries.

Free Download Hippolyte Fofack, David Bigman, "Geographical Targeting for Poverty Alleviation: Methodology and Applications"
English | 2000 | pages: 323 | ISBN: 0821346253 | PDF | 2,7 mb
‘..in many developing countries, there are large differences in economic conditions and the standard of living between regions, and even between communities within the same region. In many countries, poverty has a clear geographic dimension, since the poor are often concentrated in pockets of poverty. Therefore, the design of poverty alleviation policies must also have a signficant spatial component.’ Although development projects are carefully designed and meticulously evaluated for cost effectiveness and benefits, too many of them are not sufficiently targeted geographically. The growing availability and use of spatial data, organized in a computer system such as a geographical information system (GIS), makes it more feasible to analyze the impact of projects in specific locales and to achieve more effective targeting. ‘Geographical Targeting for Poverty Alleviation’ introduces the basic concepts of a GIS. It also demonstrates how to organize geographic and nongeographic data. In addition, it presents different methods for using the data of the Household Income and Expenditure Survey, together with other surveys and the population census, to provide estimates for the standard of living and the incidence of poverty incidence in different geographical areas of a country. Ultimately, these estimates should be used to establish guidelines for targeting poverty alleviation projects. This publication illustrates different GIS applications for identifying the project’s target population, determining the project’s spatial ‘sphere of influence’ or deciding where to locate public facilities. This publication is of interest to task managers, economists, development researchers, and geographers.

Free Download Tetyana (Tanya) Krupiy, "A Toolbox for the Application of the Rules of Targeting Ed 2"
English | ISBN: 1527509036 | 2018 | 464 pages | PDF | 2 MB
How military commanders interpret the rules of targeting impacts not only on whether civilians and civilian objects are harmed in the course of a military operation, but also on the scale of harm that ensues. Commentators have queried whether military commanders observed the law even when parties to a conflict acted in accordance with mandates to protect civilians, as was the case when a coalition of states bombed targets in Libya in 2011. However, limited guidance is publicly available on how military commanders apply these rules on the battlefield. In order to allow military commanders to exercise judgment in determining what steps they are required to take to spare civilians in a specific set of circumstances, the rules of targeting are formulated in an open-ended fashion, which complicates ones ability to evaluate whether a particular military operation complies with the law. By examining case studies ranging from Operation Desert Storm in 1991 to Operation Protective Edge in 2014, this book addresses lacunae in current scholarship. It puts forward principles which capture how military commanders deliberate while interpreting what the rules of targeting require in particular scenarios. International humanitarian law, this book contends, places a duty on attackers to assume risk in order to mitigate danger to civilians. Drawing on the field of psychology, this study provides an explanation of how military commanders assess when circumstances do not permit them to inform civilians about a forthcoming attack.

Free Download Money Stock Control and Inflation Targeting in Germany: A State Space Modelling Approach to the Bundesbank’s Operating Procedures and Intermediate Strategy By Dr. Claus Brand (auth.)
2001 | 174 Pages | ISBN: 3790813931 | PDF | 4 MB
The book considers issues relevant to the European Central Bank in refining and communicating its strategy. It offers a historical assessment of the Bundesbank’s strategy of monetary targeting conducted from 1974 to 1998. In contrast to several other prominent studies it is argued that money played a flexible but very important role in the conduct of its policy. It also explores the implications of the identified monetary policy regime in the context of various theories of the money supply process.The empirical analysis conducted in this study is based on a linear state space modelling approach which offers an appealing and direct representation of common stochastic trends. The framework is less restrictive and it is encompassing in that it does not construe the persistent dynamics as being driven by pure random walk components.

Free Download Niko Velikov – The Targeting Academy.
I discovered a new advertising approach that helps you generate more leads, book more appointments, and make more sales than ever before. And this is the exact approach that allows me to book calls for $39.46 each, and I was able to reduce the cost per purchase for my campaigns from more than $240.23 per purchase to $72.20.
With this approach, I’m generating leads for $1.46 and driving sales for just $4.48! You’ll see the proof below.. That’s the same exact approach I’m using to get you to read this page right now! It’s pretty cool, right?

Free Download Targeting Epigenetics in Inflammatory Lung Diseases by Gaurav Gupta, Brian G. Oliver, Kamal Dua, Md Khadem Ali, Piyush Dave
English | PDF EPUB (True) | 2023 | 276 Pages | ISBN : 9819947790 | 21.2 MB
This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.

Free Download Carolyn Turpin-Petrosino, "Islamophobia and Acts of Violence: The Targeting and Victimization of American Muslims "
English | ISBN: 0190922311 | 2022 | 240 pages | EPUB, PDF | 4 MB + 8 MB
Islamophobia and Acts of Violence: The Targeting and Victimization of American Muslims is a collection of perspectives by authors from a variety of academic disciplines such as legal studies, communication studies, political science, and criminology on the subject of Anti-Muslim hate crimes.

Free Download Niko Velikov – The Targeting Academy Download Links 2023 ⭐✅ ⭐✅
Here’s what you’re going to learn:

MODULE 1

Introduction To Facebook Advertising
In the first module, we will focus on the fundamentals of Facebook advertising. We’re going to discuss the power of Facebook™ ads and the most important things you need to know before you start advertising. Many people dive straight into running ads, but this first module will be essential to your success.
We are going to cover.
Overview of Social Media Advertising and Why It’s So Effective Overview of Different Types of Ads (Image Ads, Video Ads, Carousel Ads, etc.) Introduction to Targeting Options (e.g. Location, Age, Gender, Interests, Behaviors, etc.) How the Advertising Algorithm Works and How To Use It To Drive More Leads & Sales