Tag: Therapy

Free Download Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy: A Comprehensive Guide
English | 2024 | ISBN: 3031677420 | 492 Pages | PDF EPUB (True) | 134 MB
This new edition is a fully updated, comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients.

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Free Download Flora Fitzgerald, "Photodynamic Therapy: Principles, Mechanisms and Applications"
English | ISBN: 1536119121 | 2017 | 223 pages | PDF | 6 MB
In Chapter One, the basic mechanisms, applications and functional nanomaterials-based drug delivery systems for photodynamic therapy of cancer are reviewed. Chapter Two summarizes the application of different carbon based nanomaterials as agents for PDT and discusses current state-of-the-art use of fullerenes and their derivatives, carbon nanotubes and graphene quantum dots in PDT. Chapter Three covers the benefits and pitfalls of using chemi- and bioluminescent systems as intracellular excitation sources in PDT. Bioluminescence is a widespread natural phenomenon, which consists on emission of light resulting from the oxidation of a substrate in a reaction catalyzed by an enzyme in a biological system. Chapter Four addresses in the synthesis, characterization, and photodynamic activity of a novel hydrophobic photosensitizer 5,10,15,20-tetrakis(benzothiophene) Porphyrin (BTP) and water soluble photosensitizer 5,10,15,20-Tetrakis(7- sulfonatobenzothiophene) Porphyrin (SBTP). Chapter Five discusses the "Guidelines for Gastroenterological Endoscopy in Patients on Oral Antithrombotic Treatment" established by the Japan Gastroenterological Endoscopy Society (JGES).These guidelines classify endoscopic interventions according to the risk of hemorrhage and specify the management of various antithrombotic drugs. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are classified as high-risk procedures for hemorrhage, but PDT is not included in the guidelines. Because PDT causes ischemic necrosis of tumor tissue, the authors say this could possibly be performed safely in patients on oral antithrombotic therapy. The authors of Chapter Six developed a method of the initial concentration of protoporphyrin-IX in the operated removing glioblastoma tissue using the calibration curve of the fluorescent intensity and the known Pp-IX concentration in order to estimate of the more correlated with the cure rate.[/center]
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Free Download Imaging and Focal Therapy of Early Prostate Cancer
English | 2024 | ISBN: 3031667530 | 525 Pages | PDF EPUB (True) | 136 MB
This book encompasses an up-to-date, comprehensive review of the state-of-the-art for prostate gland preserving therapies. It provides insight into the latest research and clinical applications of image-guided diagnosis and minimally invasive focal, gland-preserving treatment for prostate cancer. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, image-targeted therapy methods.

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Free Download Cancer Neutron Capture Therapy By Yutaka Mishima (auth.), Yutaka Mishima (eds.)
1996 | 920 Pages | ISBN: 1475795696 | PDF | 33 MB
There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.

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Free Download Epigenetic Mechanisms in Breast Cancer Therapy and Resistance
English | 2024 | ISBN: 3031666852 | 111 Pages | PDF EPUB (True) | 21 MB
Epigenetic mechanisms are essential for normal mammalian development and maintenance of gene expression patterns. Disruption of epigenetic processes can lead to altered transcriptional regulation, gene levels, and malignant cellular transformation. Global alterations of the epigenetic landscape are a hallmark of tumorigenesis and metastasis. Conventionally, cancer was thought to be a genetic disease, but recent advancement in the field identified an abundance of epigenetic abnormalities along with genetic alterations. The extensive reprogramming of epigenetic machinery in cancer includes DNA methylation, histone modifications, nucleosome positioning and non-coding RNAs, specifically microRNA expression. Additionally, the reversible nature of epigenetic aberrations has led to the emergence of the promising field of epigenetic therapy, and recent FDA approval of epigenetic drugs for cancer treatment.

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Free Download Hazel Josh, "Cognitive Behavioral Therapy: Managing Anxiety, Depression, Eating Disorders and Panic Attacks, CBT Workbook "
English | ISBN: 1728996341 | 2018 | 161 pages | EPUB | 193 KB
♦♦Bonus: Buy the Paperback version of this book, and get the kindle eBook version included for FREE**

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Free Download Ncrp Publications, "Management of Radionuclide Therapy Patients"
English | 2006 | pages: 266 | ISBN: 0929600924 | PDF | 2,6 mb
This report, which was developed under the auspices of Program Area Committee 4 of the National Council on Radiation Protection and Measurements, examines radiation protection in medicine. It supersedes NCRP Report No. 37, Precautions in the Management of Patients Who Have Received Therapeutic Amounts of Radionuclides, issued in 1970. It provides guidance for physicians, medical and health physicists, nuclear pharmacists, health care professionals, and visitors to medical facilities. It confirms the recommendations of the NCRP Commentary No. 11, on Dose Limits for Individuals Who Receive Exposure from Radionuclide Therapy Patients, and other publications. The report discusses the basic principles of radiopharmaceutical therapy and brachytherapy, safety principles, including patient-release instructions, facility design for nuclear-medicine and radiation-oncology installations, and changes in patient status. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

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Free Download Embodied Online Therapy
Amelia Rizzo, Emanuela Gatto
English | 2024 | ISBN: 9798891135376 | 89 Pages | PDF | 4 MB

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Free Download Gene Therapy for Neurological Disorders: Molecular Approaches for Targeted Treatment
English | 2025 | ISBN: 1774916789 | 238 Pages | PDF (True) | 28 MB
Neurological illnesses pose one of the biggest hazards to the healthcare system today. This new book brings together the latest methods of gene therapy that can be used to treat both inherited and sporadic neurodegenerative diseases. It presents the most significant advances in gene transfer methods as well as the most recent understandings of the mechanisms behind specific neurodegenerative illnesses, placing these into the context of gene therapy approaches for the central nervous system. The book introduces the basics of neurodegenerative conditions and the physiological basis for their occurrence in humans. It also discusses the various proteins useful in neuro diseases and their viral applications. The book explores how stem cells can be used to learn about the future of gene therapy along with the significance of the sequences that silence genes. It discusses the functions of astrocytes in different brain regions, as well as in-vivo research in gene therapy for neurodegenerative disorders.

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Free Download Daniela V. Gitlin, "Doorknob Bombshells in Therapy: The Deadline, the Brain, and Why It Is Important to End on Time"
English | ISBN: 1324052597 | 2024 | 240 pages | EPUB | 912 KB
What should a therapist do when a patient reveals critical information at the end of a session?

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