Tag: Translational

Translational Mitochondrial Medicine


Free Download Translational Mitochondrial Medicine
English | 2024 | ISBN: 3031757408 | 783 Pages | PDF EPUB (True) | 46 MB
Translational mitochondrial medicine applies the knowledge of experimental medicine in clinical practice, it is a prospective direction of the development of mitochondrial medicine. The monograph "Translational Mitochondrial Medicine" was created on the basis of rapidly developing new information about mitochondrial diseases and their disorders, is a revised and supplemented edition of the monographs: "Mitochondrial Medicine", ed. A. Gvozdjáková, Springer, 2008 and "Recent Advances in Mitochondrial Medicine and Coenzyme Q10", eds. A. Gvozdjáková, G. Cornélissen, RB Singh, NOVA Science, USA, 2018. The monograph was created as part of the book series "Advances in biochemistry in health and disease", edited by prof. Naranjan Dhalla of Winnipeg, for which we are grateful.

(more…)

Translational Methods for Parkinson’s Disease and Atypical Parkinsonism Research


Free Download Translational Methods for Parkinson’s Disease and Atypical Parkinsonism Research
English | 2025 | ISBN: 1071640828 | 299 Pages | PDF (True) | 12 MB
This volume provides readers with an overview of translational paths that can be used to study the pathophysiology of Parkinson’s Disease and atypical parkinsonism, including molecular processes, tissue integrity, and cerebral networks during inflammatory and neurodegenerative processes. The chapters in this book are organized into three parts and cover topics such as new developments of cerebral circuit characterizations and computational neuroscience for the description of the brain’s transition through disease stages; static and dynamic systemic changes with clinical and functional outcome measures; and atypical syndromes such as neurodegenerations, immunological processes, and progressive disease states. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

(more…)

Translational Perspectives in Aduitory Neuroscience Normal Aspects of Hearing


Free Download Kelly Tremblay, "Translational Perspectives in Aduitory Neuroscience: Normal Aspects of Hearing"
English | ISBN: 1597562025 | 2012 | 576 pages | EPUB | 68 MB
Virtually anything related to hearing that has a scientific basis could be included in a book so labeled, but this book is part of a mission to improve dialogue between basic and applied scientists so that health-related science can translate in many directions: from bench to bedside and vice versa. The editors are clinical audiologists as well as classically trained hearing scientists, who, are committed to the advancement of translational research. To do this, colleagues who work along each step of the scientific continuum, from basic to applied, provided information that was theoretically deep, but contextually broad. In some instances this meant pairing authors (clinicians and scientists) who would not normally write together and asking them to co-author chapters. A diverse group of students, post-docs, and scientists also interacted with the authors by asking questions and infusing comments during the review process. This process ensured both basic and applied material would be integrated. One example is the final chapter in the third book in the series on Auditory Plasticity and Auditory Training. Rather than simply review evidence of experience-related physiological changes documented in animal models, the authors chose to address the functional significance of auditory plasticity as it pertains to auditory learning . By simply revisiting the concepts of plasticity in relation to learning there has been a resurgence of interest in the area as it pertains to auditory rehabilitation. The challenge was to present the literature in a way that allowed us to ask the tough questions like Does a statistically-significant change in perception (or biology) necessarily constitute a functionally relevant change in behavior? More importantly, do the observed changes impact a person s ability to communicate? And does it impact their quality of life?

(more…)

Translational Cardiology Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techni


Free Download Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques By David J. Durgan, Martin E. Young (auth.), Cam Patterson, Monte S. Willis (eds.)
2012 | 544 Pages | ISBN: 1617798908 | PDF | 8 MB
Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

(more…)

Engineering in Translational Medicine (Repost)


Free Download Weibo Cai, "Engineering in Translational Medicine"
English | 2014 | pages: 997 | ISBN: 144714371X, 1447169956 | PDF | 21,6 mb
This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area.

(more…)

Translational Research in Pain and Itch (2nd Edition)


Free Download Translational Research in Pain and Itch
English | 2024 | ISBN: 9819989205 | 263 Pages | PDF EPUB (True) | 23 MB
This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these conditions occur. Based on these findings, a series of novel treatment strategies are currently under development, and hopefully in a few years, medical practitioners will become more confident and optimistic when facing patients with these annoying and sometimes severe disorders. The contributing authors are world-renowned research scientists, who have made significant discoveries. The book is of interest to neuroscientists, neurologists and pharmacologists in both clinical and basic medical research field.

(more…)

Translational Neurorehabilitation Brain, Behavior and Technology


Free Download Translational Neurorehabilitation: Brain, Behavior and Technology
English | 2024 | ISBN: 3031636031 | 231 Pages | PDF EPUB (True) | 14 MB
This book focuses on rehabilitation demonstrating how translational research may help clinicians in boosting neural plasticity and functional recovery. Translational Neurorehabilitation is a new interesting field that seeks to produce more meaningful, applicable rehabilitation results that directly enhance human health, performance and quality of life. As neurological diseases increase with age and people who survive a brain injury are rising, thanks to the improvement of intensive acute care, the need to appeal to neurorehabilitation will double in the next few years. Motor, cognitive and behavior approaches have changed over the years and novel tools to treat brain and spinal cord injury should be validated before translating them into clinical practice.

(more…)

Translational Research in Biomedical Sciences Recent Progress and Future Prospects


Free Download Translational Research in Biomedical Sciences: Recent Progress and Future Prospects by Krupakar Parthasarathy, Radhakrishnan Manikkam
English | PDF EPUB (True) | 2024 | 385 Pages | ISBN : 9819717760 | 61.7 MB
The main objective of translational health science is to concentrate on discovering healthcare products for all people where care gaps exist. This book examines the applications of translational research, identifies its difficulties, outlines its essential characteristics, considers healthcare management strategies, and examines the public’s perspectives today. This book assists aspiring implementation scientists in researching this area because the discipline is still relatively young for the wide range of researchers tackling the challenge of clinical and translational science, a field dedicated to examining human health and disease, interventions, and outcomes to develop new treatment approaches, devices, and modalities to improve health. This book Edition is the most authoritative and timely resource that introduces new physiological and therapeutic processes to engage the fastest-growing scientific outcomes from academic and industrial research. The chapters in this book give insights into perspectives on the field of clinical and translational science and discuss artificial intelligence in drug development and conventional and novel clinical trial designs. There is a lot of hope that using artificial intelligence (AI) will significantly advance all facets of healthcare, from diagnosis to therapy. AI is prepared to assist medical staff with various duties, including administrative workflow, clinical documentation, patient outreach, and specialist support like image analysis, medical device automation, and patient monitoring. Some of the most important uses of AI in healthcare will be covered in this book by eminent Scientists, Academicians, and Industrial persons from both clinical and non-clinical fields.

(more…)

Cell Biology and Translational Medicine, Volume 21


Free Download Cell Biology and Translational Medicine, Volume 21: Stem Cell in Lineage, Secretome Regulation and Cancer
English | 2024 | ISBN: 3031568311 | 171 Pages | PDF EPUB (True) | 28 MB
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions.

(more…)